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埃博拉疫情中以自我为中心和利他主义的未满足需求:国际防范的障碍。

Self-Centric and Altruistic Unmet Needs for Ebola: Barriers to International Preparedness.

作者信息

Van de Burgwal Linda H M, Reperant Leslie A, Osterhaus Albert D M E, Iancu Sorana C, Pronker Esther S, Claassen Eric

机构信息

1Athena Institute,Vrije Universiteit Amsterdam,Amsterdam,Netherlands.

2Artemis One Health Research Foundation,Utrecht,Netherlands.

出版信息

Disaster Med Public Health Prep. 2016 Aug;10(4):644-8. doi: 10.1017/dmp.2016.64. Epub 2016 Jun 20.

Abstract

OBJECTIVE

Barriers to international Ebola preparedness may be elucidated by identifying heterogeneities in arguments to invest in countermeasures during "peace time."

METHODS

For each patent family (related patent documents that differed only by limited alterations to the same invention) concerning Ebola and published until the end of 2014 the oldest patent document was analyzed. Grounded theory coding identified 5 unmet needs for (1) vaccines and therapies, (2) control of outbreaks in endemic areas, (3) detection and control of outbreaks in nonendemic areas, (4) better understanding of filoviruses, and (5) protection against bioterrorism. Odds ratios for unmet needs by geographic regions and institution types were compared by using Pearson's chi-square test.

RESULTS

Statistically significant heterogeneities in unmet need profiles were found. US applicants combined self-centric and altruistic arguments, focusing on medical unmet needs and bioterrorism protection. Russian and Asian applicants emphasized self-centric motives, specifically, detection and control of nonendemic outbreaks. A clear, statistically significant mismatch between industry and academia was found: whereas industrial applicants focused on bioterrorism and neglected detection and control of nonendemic outbreaks, academic applicants did the opposite.

CONCLUSIONS

This research identified heterogeneities in articulated needs between geographic regions and stakeholder types. Structural articulation of unmet needs may form the basis for attuning stakeholder engagement strategies while progression across the demand-driven value chain might necessitate international concordance. (Disaster Med Public Health Preparedness. 2016;10:644-648).

摘要

目的

通过识别“和平时期”投资应对措施的论据中的异质性,阐明国际埃博拉疫情防范的障碍。

方法

对于每一个截至2014年底公布的涉及埃博拉的专利家族(仅对同一发明有有限改动的相关专利文件),分析最古老的专利文件。扎根理论编码确定了5个未满足的需求,分别为(1)疫苗和疗法,(2)流行地区疫情的控制,(3)非流行地区疫情的检测和控制,(4)对丝状病毒的更好理解,以及(5)防范生物恐怖主义。使用Pearson卡方检验比较不同地理区域和机构类型未满足需求的优势比。

结果

发现未满足需求概况存在统计学上的显著异质性。美国申请人结合了以自我为中心和利他的论据,侧重于医学上未满足的需求和生物恐怖主义防范。俄罗斯和亚洲申请人强调以自我为中心的动机,特别是非流行地区疫情的检测和控制。发现行业和学术界之间存在明显的、统计学上显著的不匹配:工业申请人专注于生物恐怖主义,而忽视非流行地区疫情的检测和控制,学术申请人则相反。

结论

本研究确定了地理区域和利益相关者类型之间明确表达的需求存在异质性。未满足需求的结构化表达可能构成调整利益相关者参与策略的基础,而在需求驱动的价值链中推进可能需要国际协调一致。(《灾难医学与公共卫生防范》。2016年;10:644 - 648)

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