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皮肤生物力学特性:采用非侵入性方法对年龄和身体部位影响的体内评估

Skin biomechanical properties: in vivo evaluation of influence of age and body site by a non-invasive method.

作者信息

Couturaud V, Coutable J, Khaiat A

机构信息

Centre ?Étude et de Recherche en Cosmétologie, 4, Square Villaret de Joyeuse, F-75017 Paris, FranceCentre de Recherche Yves Rocher, 7-9, avenue François-Vincent Raspail, F-94117 Arcueil Cedex, France.

出版信息

Skin Res Technol. 1995 May;1(2):68-73. doi: 10.1111/j.1600-0846.1995.tb00020.x.

Abstract

BACKGROUND/AIMS: Biomechanical properties of the skin are evaluated in vivo by torsion or extension methods. We assessed their modifications as function of age, probe diameter and regional body site.

METHODS

For measuring skin extensibility (or traction), we used a non-invasive suction device on a total of 37 volunteers, consisting of (A) 14 younger women (30.1±7.6 years) and (B) 23 older women (60.2±6.5 years). Measurements were performed on three different areas with 4 different probe diameters. The parameters used were (UE ) extensibility; (UV ) plasticity; (UR ) tonicity; (UR UE ) elasticity; the difference between the lowest point of the last curve (5th) and that of the 1st is the fatiguability. Concurrently, we measured on each volunteer the microdepressionary network (mDN) length.

RESULTS

Generally, tonicity, extensibility and elasticity decreased; fatiguability increased and plasticity stayed the same; all of these factors apply regardless of age. Results are more homogenous on the volar face of the forearm and with 2, 4 and 6 mm probe diameters. As a general trend, mDN length decreases with age.

CONCLUSIONS

The knowledge of this variation is important in interpreting the results obtained after product application. Standardisation of measures with the 2-mm probe will allow product efficacy determination and the comparison of different products.

摘要

背景/目的:通过扭转或伸展方法在体内评估皮肤的生物力学特性。我们评估了它们随年龄、探头直径和身体部位的变化。

方法

为测量皮肤伸展性(或牵引力),我们对总共37名志愿者使用了一种非侵入性抽吸装置,其中包括(A)14名年轻女性(30.1±7.6岁)和(B)23名老年女性(60.2±6.5岁)。在三个不同区域使用4种不同直径的探头进行测量。所使用的参数有(UE)伸展性;(UV)可塑性;(UR)张力;(UR UE)弹性;最后一条曲线(第5条)最低点与第1条曲线最低点之间的差值为疲劳性。同时,我们测量了每名志愿者的微凹陷网络(mDN)长度。

结果

一般来说,张力、伸展性和弹性降低;疲劳性增加,可塑性保持不变;所有这些因素与年龄无关。在前臂掌面以及使用2、4和6毫米探头直径时结果更具同质性。一般趋势是,mDN长度随年龄增长而减小。

结论

了解这种变化对于解释产品应用后获得的结果很重要。使用2毫米探头进行测量标准化将有助于确定产品功效并比较不同产品。

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