Molina Ruiz Rosa M, Evans Andrew H, Velakoulis Dennis, Looi Jeffrey Cl
Universitary Hospital Fundación Alcorcón, Rey Juan Carlos University, Madrid, Spain
Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Australas Psychiatry. 2016 Dec;24(6):534-537. doi: 10.1177/1039856216654394. Epub 2016 Jun 21.
This clinical update review focuses on treatment approaches of neuropsychiatric manifestations in Parkinson's disease.
We conducted a systematic search of the literature using Pubmed and selected recent and relevant papers for this review.
Neuropsychiatric symptoms in Parkinson's disease usually require optimization of levodopa therapy as a first step. Most psychotropic drugs can be used in Parkinson's disease, however there is still lack of an evidence base due to limited studies and difficulties in diagnosis of neuropsychiatric disorders. Non-pharmacological treatments have also proved effective in Parkinson's disease. Cognitive impairment requires special consideration.
Management of neuropsychiatric manifestations in Parkinson's disease is complicated by the lack of evidence. Treatment should be individualized and benefits and risks must be balanced.
本临床最新综述聚焦于帕金森病神经精神症状的治疗方法。
我们使用PubMed对文献进行了系统检索，并为本综述挑选了近期的相关论文。
帕金森病的神经精神症状通常首先需要优化左旋多巴治疗。大多数精神药物可用于帕金森病，但由于研究有限以及神经精神障碍诊断困难，仍缺乏证据基础。非药物治疗在帕金森病中也已证明有效。认知障碍需要特别考虑。
帕金森病神经精神症状的管理因缺乏证据而变得复杂。治疗应个体化，必须权衡益处和风险。
