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研究1:对于需要气管插管的患者,无呼吸氧合是否能降低血氧饱和度下降的风险?

BET 1: Does apnoeic oxygenation reduce the risk of desaturation in patients requiring endotracheal intubation?

作者信息

Denton Gavin, Howard Laura

机构信息

Heartlands Hospital, Birmingham, UK.

Manchester Royal Infirmary, Manchester, UK.

出版信息

Emerg Med J. 2016 Jul;33(7):517-9. doi: 10.1136/emermed-2016-205965.1.

DOI:10.1136/emermed-2016-205965.1
PMID:27330180
Abstract

A shortcut review of the literature was carried out to establish whether the use of apnoeic oxygenation technique during endotracheal intubation reduces the incidence of critical desaturation. Four trials were found to be directly relevant to the three-part question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that there is emerging evidence that the use of apnoeic oxygenation decreases the incidence of critical desaturation during endotracheal intubation. Due to the heterogeneity of trials, however, further well-constructed and emergency department (ED)-based studies are probably warranted before conclusion can be drawn for daily emergency medicine practice.

摘要

开展了文献的简短回顾,以确定在气管插管期间使用无呼吸氧合技术是否会降低严重低氧饱和度的发生率。发现有四项试验与这个三部分问题直接相关。这些论文的作者、发表日期和国家、研究的患者群体、研究类型、相关结果、结果以及研究的不足之处都列成了表格。临床要点是,有新证据表明在气管插管期间使用无呼吸氧合可降低严重低氧饱和度的发生率。然而,由于试验的异质性,在能够得出适用于日常急诊医学实践的结论之前,可能需要进一步开展精心设计的、基于急诊科的研究。

相似文献

1
BET 1: Does apnoeic oxygenation reduce the risk of desaturation in patients requiring endotracheal intubation?研究1:对于需要气管插管的患者,无呼吸氧合是否能降低血氧饱和度下降的风险?
Emerg Med J. 2016 Jul;33(7):517-9. doi: 10.1136/emermed-2016-205965.1.
2
Intubation using apnoeic oxygenation to prevent desaturation: A systematic review and meta-analysis.使用无通气氧合进行插管以预防低氧血症:系统评价和荟萃分析。
J Crit Care. 2017 Oct;41:42-48. doi: 10.1016/j.jcrc.2017.04.043. Epub 2017 Apr 30.
3
Apneic oxygenation during intubation in the emergency department and during retrieval: A systematic review and meta-analysis.急诊科插管及转运过程中的窒息氧合:一项系统评价与荟萃分析。
Am J Emerg Med. 2017 Oct;35(10):1542-1546. doi: 10.1016/j.ajem.2017.06.046. Epub 2017 Jun 24.
4
Apnoeic oxygenation during intubation: a systematic review and meta-analysis.插管期间的无呼吸氧合:一项系统评价和荟萃分析。
Anaesth Intensive Care. 2017 Jan;45(1):21-27. doi: 10.1177/0310057X1704500104.
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Pre- and Apnoeic high flow oxygenation for RApid sequence intubation in The Emergency department (Pre-AeRATE): study protocol for a multicentre, randomised controlled trial.预先和无呼吸高流量氧合在急诊科快速序贯插管中的应用(Pre-AeRATE):一项多中心随机对照试验的研究方案。
Trials. 2019 Apr 4;20(1):195. doi: 10.1186/s13063-019-3305-8.
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Apnoeic oxygenation during intubation in the intensive care unit: A systematic review and meta-analysis.重症监护病房插管期间的无呼吸氧合:一项系统评价和荟萃分析。
Heart Lung. 2017 Nov-Dec;46(6):452-457. doi: 10.1016/j.hrtlng.2017.08.001. Epub 2017 Sep 12.
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Pre-oxygenation: Implications in emergency airway management.预给氧:在紧急气道管理中的意义
Am J Emerg Med. 2017 Aug;35(8):1177-1183. doi: 10.1016/j.ajem.2017.06.006. Epub 2017 Jun 8.
8
Effect of nasal or nasopharyngeal apneic oxygenation on desaturation during induction of anesthesia and endotracheal intubation in the operating room: A narrative review of randomized controlled trials.鼻内或鼻咽通气道氧合对手术室全身麻醉诱导和气管插管期间低氧血症的影响:随机对照试验的叙述性综述。
J Clin Anesth. 2018 Dec;51:1-7. doi: 10.1016/j.jclinane.2018.07.002. Epub 2018 Jul 18.
9
The effectiveness of apneic oxygenation during tracheal intubation in various clinical settings: a narrative review.不同临床环境下气管插管期间无氧通气的有效性:一项叙述性综述
Can J Anaesth. 2017 Apr;64(4):416-427. doi: 10.1007/s12630-016-0802-z. Epub 2017 Jan 3.
10
BET 2: Should real resuscitationists use airway checklists?
Emerg Med J. 2016 Jun;33(6):439-41. doi: 10.1136/emermed-2016-205871.2.

引用本文的文献

1
Apnoeic oxygenation during paediatric intubation: A systematic review.小儿插管期间的无呼吸氧合:一项系统评价。
Front Pediatr. 2022 Nov 21;10:918148. doi: 10.3389/fped.2022.918148. eCollection 2022.
2
Apnoeic Oxygenation during Simulated Difficult Intubation in Obese Patients: Comparison of Buccal Ring, Adair and Elwyn Tube Versus Nasal Cannula: A Prospective Randomized Controlled Trial.
Anesth Essays Res. 2021 Oct-Dec;15(4):408-412. doi: 10.4103/aer.aer_114_21. Epub 2022 Mar 30.
3
Transnasal Humidified Rapid Insufflation Ventilatory Exchange in children requiring emergent intubation (Kids THRIVE): a protocol for a randomised controlled trial.经鼻湿化高流量快速序贯通气在需要紧急插管的儿童中的应用(Kids THRIVE):一项随机对照试验的方案。
BMJ Open. 2019 Feb 20;9(2):e025997. doi: 10.1136/bmjopen-2018-025997.