Hwang K P, Su S C, Chiang C H
Gaoxiong Yi Xue Ke Xue Za Zhi. 1989 Jan;5(1):50-7.
From November 1987 to October 1988, seventy-seven cases diagnosed as dengue fever and confirmed by viral culture or serological examination in the Pediatric Department of Kaohsiung Medical College Hospital were studied. In nearly two thirds (64.9%) of the total cases, the ages were between 10 and 14 years old. No significant sexual difference could be found in this study. Two peaks of cases distribution occurred at November 1987 and October 1988. The major clinical manifestations of Dengue Fever were fever, headache, skin rash and cough. Nearly half of the total cases had nausea, vomiting, myalgia and skin itching. 29 cases (37.7%) had hemorrhagic complications during the course of disease. The most common features of hemorrhage was petechiae followed by epistaxis. Two cases were confirmed as hemorrhagic dengue fever and one was also dengue shock syndrome. Most (92.5%) of the cases had body temperatures over 38.5 degrees C at the onset of the disease. The mean duration of fever was 5.9 days. No fatality was found. It is concluded that eradication of vectors in the school environment might be one of the major points of disease control according to the age distribution of this study. The appearance of hemorrhagic dengue fever is a major problem and should be closely followed by clinicians and workers of public health in Taiwan.
1987年11月至1988年10月，对高雄医学院附属医院儿科诊断为登革热并经病毒培养或血清学检查确诊的77例病例进行了研究。在所有病例中，近三分之二（64.9%）的年龄在10至14岁之间。本研究未发现明显的性别差异。病例分布有两个高峰，分别出现在1987年11月和1988年10月。登革热的主要临床表现为发热、头痛、皮疹和咳嗽。几乎一半的病例有恶心、呕吐、肌痛和皮肤瘙痒。29例（37.7%）在病程中出现出血并发症。出血最常见的表现是瘀点，其次是鼻出血。2例确诊为出血性登革热，1例为登革休克综合征。大多数（92.5%）病例在疾病发作时体温超过38.5摄氏度。发热的平均持续时间为5.9天。未发现死亡病例。根据本研究的年龄分布情况得出结论，消除学校环境中的病媒可能是疾病控制的主要要点之一。出血性登革热的出现是一个主要问题，台湾的临床医生和公共卫生工作者应密切关注。
