Dubovsky D, Jacobs P
S Afr Med J. 1977 Dec 17;52(26):1061-2.
The infectious complications after induction of remission in 31 previously untreated adult patients with acute myeloid leukaemia are described. Clinically, most of the febrile episodes were associated with infection, and in 11 of the patients who died infection was the direct cause. In 6 out of these 11 the causal organism was diagnosed ante mortem. In 6 of the 15 patients who regenerated to clinical remission and who had fever the causal organism was isolated. The policy of management of fever in this group of patients is outlined.
本文描述了31例既往未接受过治疗的成年急性髓系白血病患者诱导缓解后的感染并发症。临床上,大多数发热发作与感染有关,在11例死亡患者中,感染是直接死因。在这11例患者中的6例中,生前诊断出了致病微生物。在15例恢复至临床缓解且发热的患者中,有6例分离出了致病微生物。本文概述了该组患者发热的处理策略。