De Sutter Thomas, Akand Murat, Albersen Maarten, Everaerts Wouter, Van Cleynenbreugel Ben, De Ridder Dirk, Goethuys Hans, Moris Lisa, Milenkovic Uros, Van Poppel Hendrik, Van Der Aa Frank, Joniau Steven
Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
Department of Urology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Urology, School of Medicine, Selcuk University, Konya, Turkey.
Springerplus. 2016 May 17;5:646. doi: 10.1186/s40064-016-2287-1. eCollection 2016.
We report our long-term experience with 119 cases of N-shaped orthotopic ileal neobladder.
Between March 1996 and July 2013, a total of 119 patients (102 men, 17 women) underwent cystectomy with creation of an N-shaped orthotopic ileal neobladder. The Clavien-Dindo classification score was used for grading early (<3 months postoperative), late, and pouch-related and non-pouch-related complications. Daytime and nighttime continence were evaluated for male and female patients separately, with patients subdivided in three groups: completely continent, use of ≤1 pad, and use of >1 pad.
Median follow-up was 75 months (range 3-204). Early complications (15 major, 54 minor) occurred in 39.5 % of 119 patients whereas 53.1 % presented with late complications (56 major, 39 minor; 111 patients evaluated). Urinary infection and outlet obstruction were both the most frequent early and late pouch-related complications; early non-pouch-related complications were mainly infectious and gastrointestinal, and the most common late non-pouch-related problem was wound herniation. At 12 months, 96 and 60 % of the men and 84.6 and 66.7 % of the women respectively achieved daytime and nighttime continence.
Complication rates of the N-shaped orthotopic ileal neobladder were relatively high, probably because of meticulous recording and follow-up. Daytime continence rates were better than nighttime rates. N-shaped orthotopic ileal neobladder can be a good option for urinary diversion in selected patients who undergo radical cystectomy.
我们报告了119例N形原位回肠新膀胱的长期经验。
1996年3月至2013年7月期间,共有119例患者(102例男性,17例女性)接受了膀胱切除术并创建了N形原位回肠新膀胱。采用Clavien-Dindo分类评分对早期(术后<3个月)、晚期以及与尿袋相关和与尿袋无关的并发症进行分级。分别对男性和女性患者的白天和夜间控尿情况进行评估,患者分为三组:完全控尿、使用≤1片尿垫和使用>1片尿垫。
中位随访时间为75个月(范围3 - 204个月)。119例患者中有39.5%发生早期并发症(15例严重,54例轻微),而53.1%出现晚期并发症(56例严重,39例轻微;评估了111例患者)。尿路感染和出口梗阻都是最常见的早期和晚期与尿袋相关的并发症;早期与尿袋无关的并发症主要是感染性和胃肠道并发症,最常见的晚期与尿袋无关的问题是伤口疝。在12个月时,男性分别有96%和60%、女性分别有84.6%和66.7%实现了白天和夜间控尿。
N形原位回肠新膀胱的并发症发生率相对较高,可能是由于细致的记录和随访。白天控尿率优于夜间控尿率。对于接受根治性膀胱切除术的特定患者,N形原位回肠新膀胱可以是尿流改道的一个良好选择。