Shimomura O, Takahashi M, Tsuji A, Takagi Y, Tomiguchi S, Koga Y, Kojima A, Matsumoto M, Hara M, Hirota Y
Kaku Igaku. 1989 Feb;26(2):145-53.
Factor analysis of hepatobiliary scintigraphy using 99mTc-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) was performed, and functional factor of liver parenchyma (FA-hepatogram) was obtained. Two parameters (peak time, T 1/2) were calculated from this hepatogram. A good correlation was obtained between these parameters and ICG-R15; furthermore, these parameters were prolonged in patients with normal volunteers, chronic hepatitis, compensated and decompensated liver cirrhosis in this order. Conventional hepatogram by ROI method (ROI-hepatogram) was not suitable for the evaluation of global liver function in condition such as a large intrahepatic mass, intrahepatic gall bladder, dilatation of biliary tree, and severe liver cirrhosis. But, even in such cases, FA-hepatogram was useful for the evaluation of global liver function.
使用99mTc-N-吡哆醛-5-甲基色氨酸（99mTc-PMT）对肝胆闪烁显像进行因子分析，获得了肝实质功能因子（FA-肝图）。从该肝图计算出两个参数（峰值时间，T 1/2）。这些参数与吲哚菁绿滞留率（ICG-R15）之间存在良好的相关性；此外，在正常志愿者、慢性肝炎、代偿期和失代偿期肝硬化患者中，这些参数依次延长。通过感兴趣区（ROI）法获得的传统肝图（ROI-肝图）不适用于评估肝内巨大肿块、肝内胆囊、胆管扩张和严重肝硬化等情况下的整体肝功能。但是，即使在这些情况下，FA-肝图对于评估整体肝功能也很有用。
