Adami Fernando, Figueiredo Francisco Winter Dos Santos, Paiva Laércio da Silva, Sá Thiago Hérick de, Santos Edige Felipe de Sousa, Martins Bruno Luis, Valenti Vitor Engrácia, Abreu Luiz Carlos de
Departamento de Saúde da Coletividade, Laboratório de Epidemiologia e Análise de Dados, Faculdade de Medicina do ABC, Santo André, São Paulo, Brasil.
Departamento de Saúde da Coletividade, Laboratório de Delineamento de Estudos e Escrita Científica, Faculdade de Medicina do ABC, Santo André, São Paulo, Brasil.
PLoS One. 2016 Jun 22;11(6):e0152739. doi: 10.1371/journal.pone.0152739. eCollection 2016.
The objective was to analyze rates of stroke-related mortality and incidence of hospital admissions in Brazilians aged 15 to 49 years according to region and age group between 2008 and 2012.
Secondary analysis was performed in 2014 using data from the Hospital and Mortality Information Systems and the Brazilian Institute of Geography and Statistics. Stroke was defined by ICD, 10th revision (I60-I64). Crude and standardized mortality (WHO reference) and incidence of hospital admissions per 100,000 inhabitants, stratified by region and age group, were estimated. Absolute and relative frequencies; and linear regression were also used. The software used was Stata 11.0.
There were 35,005 deaths and 131,344 hospital admissions for stroke in Brazilians aged 15-49 years old between 2008 and 2012. Mortality decreased from 7.54 (95% CI 7.53; 7.54) in 2008 to 6.32 (95% CI 6.31; 6.32) in 2012 (β = -0.27, p = 0.013, r2 = 0.90). During the same time, incidence of hospital admissions stabilized: 24.67 (95% CI 24.66; 24.67) in 2008 and 25.11 (95% CI 25.10; 25.11) in 2012 (β = 0.09, p = 0.692, r2 = 0.05). There was a reduction in mortality in all Brazilian regions and in the age group between 30 and 49 years. Incidence of hospitalizations decreased in the South, but no significant decrease was observed in any age group.
We observed a decrease in stroke-related mortality, particularly in individuals over 30 years old, and stability of the incidence of hospitalizations; and also regional variation in stroke-related hospital admission incidence and mortality among Brazilian young adults.
目的是分析2008年至2012年间15至49岁巴西人的中风相关死亡率及住院率,并按地区和年龄组进行分析。
2014年进行了二次分析,使用了医院和死亡率信息系统以及巴西地理与统计研究所的数据。中风由国际疾病分类第10版(I60-I64)定义。估计了按地区和年龄组分层的每10万居民的粗死亡率和标准化死亡率(世卫组织参考标准)以及住院率。还使用了绝对和相对频率以及线性回归。使用的软件是Stata 11.0。
2008年至2012年间,15至49岁的巴西人中有35005人死于中风,131344人因中风住院。死亡率从2008年的7.54(95%置信区间7.53;7.54)降至2012年的6.32(95%置信区间6.31;6.32)(β = -0.27,p = 0.013,r2 = 0.90)。同一时期,住院率趋于稳定:2008年为24.67(95%置信区间24.66;24.67),2012年为25.11(95%置信区间25.10;25.11)(β = 0.09,p = 0.692,r2 = 0.05)。巴西所有地区以及30至49岁年龄组的死亡率均有所下降。南部地区的住院率有所下降,但在任何年龄组中均未观察到显著下降。
我们观察到中风相关死亡率有所下降,尤其是30岁以上人群,住院率趋于稳定;并且巴西年轻成年人中风相关住院率和死亡率存在地区差异。