Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Ann Neurol. 2011 Nov;70(5):713-21. doi: 10.1002/ana.22539. Epub 2011 Sep 2.
The aim of this study was to determine acute stroke hospitalization rates for children and young adults and the prevalence of stroke risk factors among children and young adults hospitalized for acute stroke.
The study population consisted of 1995-2008 hospitalizations from the Nationwide Inpatient Sample of the Healthcare Cost and Utilization Project. Subarachnoid hemorrhage, intracerebral hemorrhage, and ischemic stroke hospitalizations were identified by the primary International Classification of Diseases, 9th ed, Clinical Modification (ICD-9-CM) code. Seven consecutive 2-year time intervals were selected. Three age groups were utilized: 5 to 14 years, 15 to 34 years, and 35 to 44 years. Stroke risk factors and comorbidities among those hospitalized with acute stroke were identified by secondary ICD-9-CM codes.
During the period of study, the prevalence of hospitalizations of acute ischemic stroke increased among all age and gender groups except females aged 5 to 14 years. Females aged 15 to 34 years and males and females aged 35 to 44 years showed a decrease in the prevalence of hospitalizations for subarachnoid hemorrhage, whereas females aged 5 to 14 years showed increases for subarachnoid hemorrhage. Hypertension, diabetes, obesity, lipid disorders, and tobacco use were among the most common coexisting conditions, and their prevalence increased from 1995 to 2008 among adolescents and young adults (aged 15-44 years) hospitalized with acute ischemic stroke.
Increases in the prevalence of ischemic stroke hospitalizations and coexisting traditional stroke risk factors and health risk behaviors were identified among acute ischemic stroke hospitalizations in young adults. Our results from national surveillance data accentuate the need for public health initiatives to reduce risk factors for stroke among adolescents and young adults.
本研究旨在确定儿童和青年人群中急性脑卒中住院率，以及因急性脑卒中住院的儿童和青年人群中脑卒中危险因素的流行率。
研究人群来自 1995 年至 2008 年医疗费用和利用项目国家住院患者样本。蛛网膜下腔出血、脑出血和缺血性脑卒中住院患者通过国际疾病分类第 9 版临床修订版（ICD-9-CM）的主要代码进行识别。选择了七个连续的两年时间间隔。使用了三个年龄组：5 至 14 岁、15 至 34 岁和 35 至 44 岁。通过 ICD-9-CM 二级代码确定了因急性脑卒中住院患者的脑卒中危险因素和合并症。
在研究期间，除了 5 至 14 岁的女性外，所有年龄和性别组的急性缺血性脑卒中住院率均有所增加。15 至 34 岁的女性和 35 至 44 岁的男性和女性的蛛网膜下腔出血住院率下降，而 5 至 14 岁的女性蛛网膜下腔出血的住院率则有所增加。高血压、糖尿病、肥胖、血脂异常和烟草使用是最常见的合并症，在 1995 年至 2008 年间，因急性缺血性脑卒中住院的青少年和青年（15 至 44 岁）中，这些合并症的患病率有所增加。
在青年人群的急性缺血性脑卒中住院患者中，缺血性脑卒中住院率以及传统脑卒中危险因素和健康风险行为的合并率有所增加。我们从国家监测数据中得出的结果强调了需要采取公共卫生措施，减少青少年和青年人群中脑卒中的危险因素。
