Kholodov A Iu, Val'dman B M, Lifshits R I, Puzhevskiĭ A S, Nalimov A G
Klin Khir (1962). 1989(3):37-9.
The comparison of sensitivity to heparin before hemosorption in burn patients with high level of the blood middle molecular peptides before the operation on the heart in patients with rheumatic cardiac defect without changes in the blood peptide level was carried out. In the model experiments, the influence of a fraction of the middle molecular peptides obtained from the blood of healthy and burned dogs on the effects of heparin and protamine sulfate, and as well on thrombocytic aggregation was studied. The role of the middle molecular peptides in the alteration of response to heparin in burn disease is discussed.
对烧伤患者血液中分子肽水平高者在血液灌流前对肝素的敏感性与风湿性心脏缺损患者在心脏手术前血液肽水平无变化者进行了比较。在模型实验中，研究了从健康犬和烧伤犬血液中获得的中分子肽部分对肝素和硫酸鱼精蛋白作用以及对血小板聚集的影响。讨论了中分子肽在烧伤疾病中对肝素反应改变中的作用。
