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男性下尿路症状的管理

Managing lower urinary tract symptoms in men.

作者信息

MacKenzie Kenneth R, Aning Jonathan J

出版信息

Practitioner. 2016 Apr;260(1792):11-6, 2.

Abstract

Male lower urinary tract symptoms (LUTS) are common and increase in prevalence with age. Up to 90% of men aged 50 to 80 may suffer from troublesome LUTS. Men may attend expressing direct concern about micturition, describing one or more LUTS and the related impact on their quality of life. Frequently men may present for other medical or urological reasons such as concern regarding their risk of having prostate cancer or erectile dysfunction but on taking a history bothersome LUTS are identified. Men may present late in the community with urinary retention: the inability to pass urine. A thorough urological history is essential to inform management. It is important to determine whether men have storage or voiding LUTS or both. All patients must have a systematic comprehensive examination including genitalia and a digital rectal examination. Investigations performed in primary care should be guided by the history and examination findings, taking into account the impact of the LUTS on the individual's quality of life. Current NICE guidelines recommend the following to be performed at initial assessment: frequency volume chart (FVC); urine dipstick to detect blood, glucose, protein, leucocytes and nitrites; and prostate specific antigen. Men should be referred for urological review if they have: bothersome LUTS which have not responded to conservative management or medical therapy; LUTS in association with recurrent or persistent UTIs; urinary retention; renal impairment suspected to be secondary to lower urinary tract dysfunction; or suspected urological malignancy. All patients not meeting criteria for immediate referral to urology can be managed initially in primary care. Based on history, examination and investigation findings an individualised management plan should be formulated. Basic lifestyle advice should be given regarding reduction or avoidance of caffeinated products and alcohol. The FVC should guide advice regarding fluid intake management and all medications should be reviewed.

摘要

男性下尿路症状(LUTS)很常见,且患病率随年龄增长而增加。在50至80岁的男性中,高达90%可能患有令人困扰的LUTS。男性前来就诊时可能会直接表达对排尿的担忧,描述一种或多种LUTS及其对生活质量的相关影响。男性常常因其他医疗或泌尿问题前来就诊,比如担心患前列腺癌或勃起功能障碍的风险,但在问诊时会发现令人困扰的LUTS。男性在社区中可能会因尿潴留(无法排尿)而就诊较晚。全面的泌尿病史对于指导治疗至关重要。确定男性是有储尿期LUTS、排尿期LUTS还是两者皆有很重要。所有患者都必须进行系统全面的检查,包括生殖器检查和直肠指检。基层医疗中进行的检查应根据病史和检查结果来指导,同时要考虑LUTS对个体生活质量的影响。目前英国国家卫生与临床优化研究所(NICE)的指南建议在初始评估时进行以下检查:频率-尿量图表(FVC);尿试纸检测血液、葡萄糖、蛋白质、白细胞和亚硝酸盐;以及前列腺特异性抗原。如果男性有以下情况,应转诊至泌尿外科进行复查:对保守治疗或药物治疗无反应的令人困扰的LUTS;与复发性或持续性尿路感染相关的LUTS;尿潴留;怀疑继发于下尿路功能障碍的肾功能损害;或疑似泌尿系统恶性肿瘤。所有不符合立即转诊至泌尿外科标准的患者最初可在基层医疗中进行管理。应根据病史、检查和检查结果制定个性化的管理计划。应就减少或避免含咖啡因产品和酒精给出基本的生活方式建议。FVC应指导关于液体摄入管理的建议,并且应审查所有药物。

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