Department of Urology, University of Tokyo, Tokyo, Japan.
BJU Int. 2012 May;109(10):1512-6. doi: 10.1111/j.1464-410X.2011.10445.x. Epub 2011 Aug 26.
Study Type - Therapy (symptom prevalence). Level of Evidence 2a. What's known on the subject? and What does the study add? The International Prostate Symptom Score (IPSS) has been most commonly used for the symptom assessment of men with lower urinary tract symptoms (LUTS). However, LUTS in men are so variable that they may not be fully captured by the IPSS questionnaire alone. This study has demonstrated that the Core Lower Urinary Tract Symptom Score (CLSS) questionnaire, which addresses 10 important symptoms, is an appropriate initial assessment tool for LUTS in men with various diseases/conditions.
International Prostate Symptom Score (IPSS) has been commonly used to assess lower urinary tract symptoms (LUTS). We have recently developed Core Lower Urinary Tract Symptom Score (CLSS). The aim of this study is to compare IPSS and CLSS for assessing LUTS in men.
Consecutive 515 men fulfilled IPSS and CLSS questionnaires. IPSS QOL Index was used as the QOL surrogate. The clinical diagnoses were BPH (n = 116), BPH with OAB wet (n =80), prostate cancer (n = 128), prostatitis (n = 68), underactive bladder (n = 8), others (n = 72), and controls (e.g., occult blood) (n = 42). Simple statistics and predictability of poor QOL (QOL Index 4 or greater) were examined.
All symptom scores were significantly increased in symptomatic men compared with controls. Scores of corresponding symptoms of two questionnaires were significantly correlated (r = 0.58-0.85, all P < 0.0001). A multivariate regression model to predict poor QOL indicated nine symptoms (daytime frequency, nocturia, urgency, urgency incontinence, slow stream, straining, incomplete emptying, bladder pain and urethral pain) as independent factors. The hazard ratios for bladder pain (2.2) and urgency incontinence (2.0) were among the highest. All the nine symptoms are addressed in CLSS, while three symptoms (urgency incontinence, bladder, and urethral pain) are dismissed in IPSS.
CLSS questionnaire is more comprehensive than IPSS questionnaire for symptom assessment of men with various diseases/conditions, although both questionnaires can capture LUTS with possible negative impact on QOL.
研究类型 - 治疗（症状流行率）。证据水平 2a。关于这个主题已经知道了什么？这项研究增加了什么？国际前列腺症状评分（IPSS）是最常用于评估下尿路症状（LUTS）的男性的症状评估方法。然而，男性的 LUTS 变化如此之大，仅凭 IPSS 问卷可能无法完全捕捉到。这项研究表明，核心下尿路症状评分（CLSS）问卷，其中包含 10 个重要症状，是评估各种疾病/状况下男性 LUTS 的合适初始评估工具。
国际前列腺症状评分（IPSS）已被广泛用于评估下尿路症状（LUTS）。我们最近开发了核心下尿路症状评分（CLSS）。本研究的目的是比较 IPSS 和 CLSS 评估男性 LUTS。
连续 515 名男性完成了 IPSS 和 CLSS 问卷。IPSS QOL 指数被用作 QOL 的替代指标。临床诊断为 BPH（n = 116）、BPH 伴 OAB 湿（n = 80）、前列腺癌（n = 128）、前列腺炎（n = 68）、膀胱过度活动症（n = 8）、其他（n = 72）和对照组（例如，潜血）（n = 42）。检查了简单统计和不良 QOL（QOL 指数为 4 或更高）的预测性。
与对照组相比，所有症状评分在有症状的男性中均显着增加。两个问卷的相应症状评分显着相关（r = 0.58-0.85，均 P <0.0001）。预测不良 QOL 的多变量回归模型表明，九个症状（白天尿频、夜间尿频、尿急、急迫性尿失禁、尿流缓慢、用力排尿、排尿不完全、膀胱疼痛和尿道疼痛）是独立因素。膀胱疼痛（2.2）和急迫性尿失禁（2.0）的风险比最高。CLSS 问卷涵盖了所有九个症状，而 IPSS 问卷则忽略了三个症状（急迫性尿失禁、膀胱和尿道疼痛）。
CLSS 问卷比 IPSS 问卷更全面地评估各种疾病/状况男性的症状，尽管两个问卷都可以捕捉到可能对 QOL 产生负面影响的 LUTS。
