Lindvall M, Edvinsson L, Owman C
Acta Physiol Scand Suppl. 1977;452:77-86.
Histochemical studies have shown that the rabbit choroid plexus receives a well-developed adrenergic and cholinergic nerve supply. The adrenergic innervation, which orginates almost entirely from the superior cervical sympathetic ganglia, begins to develop around birth and is fully established 3 weeks later. Electron microscopy has shown that the nerve terminals innervate both the plexus arterioles and its secretory epithelium. The sympathetic fibres have been shown to influence the plexus epithelium, as reflected by their effect on its carbonic anhydrase activity. They appear to have an inhibitory effect on the bulk CSF production, as revealed by electrical nerve stimulation and denervation experiments. The control seems to be excerted primarily on the plexus epithelium, though some of the effect may also be associated with alteration in choroid plexus blood flow.
组织化学研究表明，兔脉络丛接受发育良好的肾上腺素能和胆碱能神经支配。肾上腺素能神经支配几乎完全起源于颈上交感神经节，在出生前后开始发育，并在3周后完全建立。电子显微镜显示，神经末梢支配丛小动脉及其分泌上皮。已表明交感神经纤维会影响丛上皮，这可从其对碳酸酐酶活性的影响中得到反映。如电刺激神经和去神经实验所示，它们似乎对脑脊液的大量生成具有抑制作用。这种控制似乎主要作用于丛上皮，尽管部分作用也可能与脉络丛血流的改变有关。
