Suárez J P, Domínguez M L, Gómez M A, Muñoz J L
Servicio de Medicina Nuclear, Hospital San Pedro de Alcántara, Cáceres, España.
Servicio de Medicina Nuclear, Hospital San Pedro de Alcántara, Cáceres, España.
Rev Esp Med Nucl Imagen Mol. 2017 Jan-Feb;36(1):48-52. doi: 10.1016/j.remn.2016.05.005. Epub 2016 Jun 20.
Spontaneous intracranial hypotension is a clinical syndrome caused by a loss of cerebrospinal fluid volume, usually secondary to leaking through structural defects of the spinal dura mater. Radioisotope cisternography (RC) can confirm the diagnosis of spontaneous intracranial hypotension, especially in doubtful or atypical case presentations. A retrospective study was conducted on 8 patients who underwent RC because spontaneous intracranial hypotension was suspected, and they presented with atypical clinical manifestations and/or inconclusive findings in other imaging techniques. RC detected paradural extravasation of cerebrospinal fluid in 7 patients. Moreover, there was indirect evidence of cerebrospinal fluid leaks in all 8 patients (early appearance of radioactivity in the bladder, soft tissue uptake of radioisotope and/or reduction in the amount of radiotracer in the brain at 24hours). RC had a significant impact on the diagnosis of 6 patients, and on the therapeutic management of 4 patients.
自发性颅内低压是一种由脑脊液量减少引起的临床综合征，通常继发于通过硬脊膜结构缺陷的渗漏。放射性核素脑池造影（RC）可以确诊自发性颅内低压，尤其是在可疑或非典型病例表现中。对8例因怀疑自发性颅内低压而接受RC检查的患者进行了回顾性研究，这些患者表现出非典型临床表现和/或其他成像技术检查结果不明确。RC检测到7例患者硬膜外脑脊液外渗。此外，所有8例患者均有脑脊液漏的间接证据（膀胱放射性早期出现、放射性核素软组织摄取和/或24小时时脑内放射性示踪剂减少）。RC对6例患者的诊断有显著影响，对4例患者的治疗管理有显著影响。
