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骨折固定的稳定性何时会受到骨质疏松性骨的限制?

When is the stability of a fracture fixation limited by osteoporotic bone?

作者信息

Konstantinidis Lukas, Helwig Peter, Hirschmüller Anja, Langenmair Elia, Südkamp Norbert P, Augat Peter

机构信息

Klinik für Orthopädie und Unfallchirurgie, Universitätsklinik Freiburg, Hugstetterstr. 55, 79106Freiburg, Germany.

Institut für Biomechanik, Berufsgenossenschaftliche Unfallklinik Murnau & Paracelsus Medical University, Salzburg, Prof. Kuentscher Str. 8, 82418Murnau, Germany.

出版信息

Injury. 2016 Jun;47 Suppl 2:S27-32. doi: 10.1016/S0020-1383(16)47005-1.

Abstract

This article is concerned with the search for threshold values for bone quality beyond which the risk of fixation failure increased. For trochanteric fractures we recognized a BMD lower than 250mg/cm(3) as an additional risk for cut out. For medial femoral neck fractures since joint replacement surgery is available and produces excellent functional results, we see no indication for further differentiation or analysis of bone quality in relation to fracture fixation. In the area of osteoporotic vertebral body fractures, there are many experimental studies that try to identify BMD limits of screw fixation in the cancellous bone on the basis of QCT analysis. However, these values have not yet been introduced for application in clinical practice. In case of indication for surgical fixation, we favor minimally invasive, bisegmental, fourfold dorsal instrumentation with screw-augmentation for a T-value less than -2.0 SD (DXA analysis, total hip or total lumbar spine). For proximal humerus fractures, BMD value of 95mg/cm(3) could be seen as a threshold value below which the risk of failure rises markedly. In relation to osteoporotic distal radius fractures, based on our clinical experience and scientific analyses there are virtually no restrictions as far as bone quality is concerned on the application of palmar locking implants in the surgical management of distal radius fractures. Optimization of preoperative diagnostics might help to revise the treatment algorithm to take bone density into account, thus reducing the risk of failure and, at the same time, acquiring additional data for future reference.

摘要

本文关注的是寻找骨质量的阈值,超过该阈值固定失败风险会增加。对于转子间骨折,我们认为骨密度低于250mg/cm³是内固定物穿出的额外风险因素。对于股骨内侧颈骨折,由于可进行关节置换手术且功能效果良好,我们认为没有必要进一步区分或分析与骨折固定相关的骨质量。在骨质疏松性椎体骨折领域,有许多实验研究试图基于定量CT分析确定松质骨中螺钉固定的骨密度极限。然而,这些数值尚未引入临床实践应用。如果有手术固定指征,对于T值小于 -2.0标准差(双能X线吸收法分析,全髋或全腰椎)的情况,我们倾向于采用微创、双节段、四点背侧内固定并辅以螺钉强化。对于肱骨近端骨折,95mg/cm³的骨密度值可视为一个阈值,低于该值失败风险会显著增加。对于骨质疏松性桡骨远端骨折,根据我们的临床经验和科学分析,在桡骨远端骨折手术治疗中应用掌侧锁定钢板时,在骨质量方面几乎没有限制。优化术前诊断可能有助于修订治疗方案以考虑骨密度,从而降低失败风险,同时获取额外数据以供未来参考。

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