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无麸质饮食对难治性肾病综合征儿童的影响。

The Effect of a Gluten-Free Diet in Children With Difficult-to-Manage Nephrotic Syndrome.

作者信息

Lemley Kevin V, Faul Christian, Schramm Karla, Meyers Kevin, Kaskel Frederick, Dell Katherine M, Gipson Debbie S, Gibson Keisha, Trachtman Howard

机构信息

Division of Nephrology, Children's Hospital Los Angeles, Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, California;

Division of Nephrology and Hypertension, Department of Medicine and Department of Cell Biology and Anatomy, University of Miami Leonard M. Miller School of Medicine, Miami, Florida;

出版信息

Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2015-4528.

Abstract

Case reports have linked childhood nephrotic syndrome to food sensitivity, including gluten. We report our experience with 8 children (6 boys, 2 girls; age at implementation of special diet 2-14 years) with difficult-to-manage nephrotic syndrome who were placed on a gluten-free diet for 3.4 ± 4.3 years (range, 0.6-14 years) and who had clinical improvement enabling reduction or discontinuation in steroid dosage.

摘要

病例报告已将儿童肾病综合征与食物敏感性(包括麸质)联系起来。我们报告了8名儿童(6名男孩,2名女孩;开始特殊饮食时的年龄为2至14岁)的经验,这些儿童患有难以控制的肾病综合征,他们接受了3.4±4.3年(范围为0.6至14年)的无麸质饮食,并且临床症状有所改善,使得类固醇药物剂量得以减少或停用。

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本文引用的文献

1
The intestine-renal connection in IgA nephropathy.IgA肾病中的肠-肾联系。
Nephrol Dial Transplant. 2015 Mar;30(3):360-6. doi: 10.1093/ndt/gfu343. Epub 2014 Nov 11.
3
Childhood nephrotic syndrome in the 21st century: What's new?21世纪的儿童肾病综合征:有哪些新进展?
J Paediatr Child Health. 2015 May;51(5):497-504. doi: 10.1111/jpc.12734. Epub 2014 Sep 30.
4
Celiac disease: a review.乳糜泻:综述。
JAMA Pediatr. 2014 Mar;168(3):272-8. doi: 10.1001/jamapediatrics.2013.3858.
10
Management of childhood onset nephrotic syndrome.儿童期肾病综合征的管理
Pediatrics. 2009 Aug;124(2):747-57. doi: 10.1542/peds.2008-1559. Epub 2009 Jul 27.

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