Lemley Kevin V, Faul Christian, Schramm Karla, Meyers Kevin, Kaskel Frederick, Dell Katherine M, Gipson Debbie S, Gibson Keisha, Trachtman Howard
Division of Nephrology, Children's Hospital Los Angeles, Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, California;
Division of Nephrology and Hypertension, Department of Medicine and Department of Cell Biology and Anatomy, University of Miami Leonard M. Miller School of Medicine, Miami, Florida;
Pediatrics. 2016 Jul;138(1). doi: 10.1542/peds.2015-4528.
Case reports have linked childhood nephrotic syndrome to food sensitivity, including gluten. We report our experience with 8 children (6 boys, 2 girls; age at implementation of special diet 2-14 years) with difficult-to-manage nephrotic syndrome who were placed on a gluten-free diet for 3.4 ± 4.3 years (range, 0.6-14 years) and who had clinical improvement enabling reduction or discontinuation in steroid dosage.
病例报告已将儿童肾病综合征与食物敏感性(包括麸质)联系起来。我们报告了8名儿童(6名男孩,2名女孩;开始特殊饮食时的年龄为2至14岁)的经验,这些儿童患有难以控制的肾病综合征,他们接受了3.4±4.3年(范围为0.6至14年)的无麸质饮食,并且临床症状有所改善,使得类固醇药物剂量得以减少或停用。