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胰腺癌的先进内镜治疗方法。

State-of-the-art endoscopic procedures for pancreatic cancer.

机构信息

University of Chicago Medicine, Gastroenterology, Hepatology & Nutrition, Chicago, IL, USA.

University of Chicago Medicine, Center for Endoscopic Research & Therapeutics, Chicago IL, USA.

出版信息

Future Oncol. 2016 Sep;12(17):2037-47. doi: 10.2217/fon-2016-0123. Epub 2016 Jun 24.

Abstract

Pancreatic cancer is the twelfth most common cancer worldwide, taking the fourth place in cancer-related mortality in western countries. Despite significant efforts in understanding the tumor biology of pancreatic cancer and introducing new technologies and therapies to improve the detection, staging and treatment of this disease, pancreatic cancer continues to have a high and almost unchanged mortality. In the last few decades, the development of techniques such as endoscopic retrograde cholangio pancreatography and endoscopic ultrasound have allowed us to directly access the pancreaticobiliary system and fight pancreatic cancer and its complications from different fronts. Our goal with this review is to discuss the most cutting-edge endoscopic techniques available in our armamentarium to diagnose, stage and treat pancreatic cancer.

摘要

胰腺癌是全球第十二大常见癌症,在西方国家的癌症相关死亡率中排名第四。尽管在了解胰腺癌的肿瘤生物学方面做出了巨大努力,并引入了新技术和疗法来改善对这种疾病的检测、分期和治疗,但胰腺癌的死亡率仍然很高,且几乎没有变化。在过去的几十年中,内镜逆行胰胆管造影术和内镜超声等技术的发展使我们能够直接进入胰胆管系统,从不同方面对抗胰腺癌及其并发症。我们撰写这篇综述的目的是讨论目前可用于诊断、分期和治疗胰腺癌的最先进的内镜技术。

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