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[菲拉托夫组织疗法制剂免疫药理活性的初步筛选]

[Primary screening of the immunopharmacologic activity of Filatov tissue therapy preparations].

作者信息

Degtiarenko T V, Ivanova A S, Skvortsov V Iu, Masternak T V, Larin A S

出版信息

Oftalmol Zh. 1989(1):34-9.

PMID:2733969
Abstract

The paper presents results of primary assessment of immunopharmacologic activity of tissue preparations (peloidodistillate, FiBS, torfot, extract of aloe, placental extract) and the study of their influence on basic links of immune response (experimental investigations were carried out with mice-hybrids F1). It is found that the studied bioregulators possess immunomodulating action on primary humoral immune response and don't increase a hypersensitive reaction of a slowed type. The direction of immunotropic action of tissue preparations depends on the state of immunologic reactivity of the body and the kind of a preparation (variety of immunopharmacologic activity of the distillates groups and albumin preparations). It is expedient to work out indications to the usage of tissue preparations after V. P. Filatov to prevent and treat immunodeficient and immunopathologic conditions of the body.

摘要

本文介绍了组织制剂(泥煤馏出物、FiBS、托尔福特、芦荟提取物、胎盘提取物)免疫药理活性的初步评估结果,以及它们对免疫反应基本环节影响的研究(以F1代小鼠杂交种进行实验研究)。结果发现,所研究的生物调节剂对初次体液免疫反应具有免疫调节作用,且不会增加迟发型超敏反应。组织制剂免疫otropic作用的方向取决于机体免疫反应性的状态以及制剂的种类(馏出物组和白蛋白制剂免疫药理活性的多样性)。制定使用V.P.菲拉托夫组织制剂预防和治疗机体免疫缺陷和免疫病理状况的适应症是适宜的。

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