Shimizu M, Hayashi T, Itoh H, Saitoh Y
First Department of Surgery, Kobe University School of Medicine, Japan.
Pancreas. 1989;4(3):375-7. doi: 10.1097/00006676-198906000-00016.
Acute terminal pancreatitis (ATP) was defined as a postmortem entity of localized acute pancreatitis without any clinical evidence of pancreatic disease. Based on the deliberate examinations of pancreatic tissue from 76 autopsies, we found 10 cases (13%) that met the criteria of ATP. Shock as an immediate cause of death was a statistically significant factor in our cases of ATP. There were two pathological types of ATP, one periductal and the other perilobular. These two types of ATP implied that there would be at least two different mechanisms for the development of acute pancreatitis: pancreatic duct and periduct damage, and acinar cell injury at the periphery of lobules.
急性终末期胰腺炎(ATP)被定义为一种局限性急性胰腺炎的尸检实体,且无任何胰腺疾病的临床证据。基于对76例尸检胰腺组织的仔细检查,我们发现10例(13%)符合ATP标准。休克作为直接死因在我们的ATP病例中是一个具有统计学意义的因素。ATP有两种病理类型,一种是导管周围型,另一种是小叶周围型。这两种类型的ATP表明急性胰腺炎的发生至少有两种不同机制:胰管和导管周围损伤,以及小叶周边腺泡细胞损伤。