Smith Lynne M, Santos Lucinda S
Department of Pediatrics, Los Angeles Biomedical Institute at Harbor-UCLA Medical Center and David Geffen School of Medicine at UCLA, Los Angeles, California.
Birth Defects Res C Embryo Today. 2016 Jun;108(2):142-6. doi: 10.1002/bdrc.21131.
Prenatal substance use remains a significant issue in the United States. Initial reports regarding prenatal cocaine and methamphetamine exposure suggested profound adverse effects on child development. However, subsequent prospective, longitudinal investigations have found more subtle effects. What follows is a brief review of the health, growth, behavioral, and intellectual outcomes for children exposed to prenatal cocaine and prenatal methamphetamine. Factors that may mitigate or intensify subtle adverse effects manifested in exposed children will also be discussed. Birth Defects Research (Part C) 108:142-146, 2016. © 2016 Wiley Periodicals, Inc.
在美国，孕期使用药物仍然是一个重大问题。关于孕期可卡因和甲基苯丙胺暴露的初步报告表明，这对儿童发育有严重的不良影响。然而，随后的前瞻性纵向研究发现了更为细微的影响。以下是对孕期接触可卡因和孕期接触甲基苯丙胺的儿童的健康、生长、行为和智力结果的简要综述。还将讨论可能减轻或加剧受暴露儿童所表现出的细微不良影响的因素。《出生缺陷研究》（C部分）108:142 - 146，2016年。© 2016威利期刊公司。
