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在护理点将患者偏好纳入前列腺癌男性的治疗决策中。

Integrating Patient Preference into Treatment Decisions for Men with Prostate Cancer at the Point of Care.

机构信息

Department of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Department of Urology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Lineberger Comprehensive Cancer Center, Cancer Outcomes Research Group, Multidisciplinary Genitourinary Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

出版信息

J Urol. 2016 Dec;196(6):1640-1644. doi: 10.1016/j.juro.2016.06.082. Epub 2016 Jun 23.

Abstract

PURPOSE

Men with clinically localized prostate cancer face an archetypal "preference sensitive" treatment decision. A shared decision making process incorporating patient values and preferences is paramount. We evaluated the benefit of a novel decision making application, and investigated associations between patient preferences and treatment choice.

MATERIALS AND METHODS

We used a novel, web based application that provides education, preference measurement and personalized decision analysis for patients with newly diagnosed prostate cancer. Preferences are measured using conjoint analysis. The application ranks treatment options according to their "fit" (expected value) based on clinical factors and personal preferences, and serves as the basis for shared decision making during the consultation. We administered the decisional conflict scale before and after completion of the application. Additionally, we compared post-visit perceptions of shared decision making between a baseline "usual care" cohort and a cohort seen after the application was integrated into clinical practice.

RESULTS

A total of 109 men completed the application before their consultation, and had decisional conflict measured before and after use. Overall decisional conflict decreased by 37% (p <0.0001). Analysis of the decisional conflict subscales revealed statistically significant improvements in all 5 domains. Patients completing the decision making application (33) felt more included in (88% vs 57%, p=0.01) and jointly responsible for (94% vs 52%, p <0.0001) the decision about further treatment compared to those receiving usual care (24). More patients who completed the application strongly agreed that different treatment options were discussed (94% vs 74%, p=0.02).

CONCLUSIONS

Implementation of this web based intervention was associated with decreased decisional conflict and enhanced elements of shared decision making.

摘要

目的

患有临床局限性前列腺癌的男性面临典型的“偏好敏感”治疗决策。纳入患者价值观和偏好的共同决策过程至关重要。我们评估了一种新的决策应用程序的益处,并研究了患者偏好与治疗选择之间的关联。

材料和方法

我们使用了一种新的基于网络的应用程序,该应用程序为新诊断为前列腺癌的患者提供教育、偏好测量和个性化决策分析。使用联合分析来衡量偏好。该应用程序根据临床因素和个人偏好对治疗选择进行排名,根据“适合度”(预期值)进行排名,并作为咨询过程中共同决策的基础。我们在完成应用程序前后使用决策冲突量表进行测量。此外,我们比较了在将应用程序整合到临床实践前后,基线“常规护理”队列和接受应用程序后就诊的队列之间的共同决策感知。

结果

共有 109 名男性在就诊前完成了应用程序,并在使用前后测量了决策冲突。总体决策冲突降低了 37%(p <0.0001)。决策冲突子量表的分析显示,所有 5 个领域均有统计学显著改善。与接受常规护理的患者(24 名)相比,完成决策制定应用程序(33 名)的患者感到自己更被包括在内(88%比 57%,p=0.01),并共同负责(94%比 52%,p <0.0001)进一步治疗的决策。更多完成应用程序的患者强烈认为讨论了不同的治疗选择(94%比 74%,p=0.02)。

结论

实施这种基于网络的干预措施与降低决策冲突和增强共同决策的各个方面有关。

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