Roche P W, Failbus S, Britton W
Trop Doct. 1989 Apr;19(2):59-61. doi: 10.1177/004947558901900205.
The self administration of dapsone by Nepali leprosy patients receiving multidrug therapy was assessed by a colorimetric and a filter paper spot test. Overall 45 out of 337 (13.3%) patients were found to be non-compliant. The relation of non-compliance to sex, age, leprosy classification, therapy type and length of therapy was investigated. The spot test was compared with the colorimetric assay and found to have a relative sensitivity of 99.3% and specificity of 95.4%. Follow up of patients was successful in that two-thirds of non-compliant patients were compliant on their follow-up test.
通过比色法和滤纸斑点试验对接受多药疗法的尼泊尔麻风病患者自行服用氨苯砜的情况进行了评估。在337名患者中，总共发现45名（13.3%）患者未遵医嘱服药。研究了不服药与性别、年龄、麻风病分类、治疗类型和治疗时长之间的关系。将斑点试验与比色测定法进行比较，发现其相对灵敏度为99.3%，特异性为95.4%。对患者的随访取得了成功，因为三分之二未遵医嘱服药的患者在随访测试中做到了遵医嘱服药。
