Veranian O A, Volkova N A, Karpliuk I A
Vopr Pitan. 1989 Mar-Apr(2):33-7.
A study was made of the effect produced by cadmium on the body under the conditions of different protein content in the diet. Experiments made on white rats lasted 6 months. There were one control and 3 experimental groups kept on isocaloric semi-synthetic diets which differed only in the protein content. The optimal diet contained 18 percent of protein, the excess one 30 percent, and the deficient one 5 percent. All the experimental animals received 100 micrograms/kg cadmium chloride with the diet on a daily basis, which provoked cadmium intoxication. In the course of experiments, the animals were examined for the general health status and body weight, for the general health status and body weight, for renal, liver and spermatozoal functions as well as for cadmium metabolism. The kidneys, liver and testes were subjected to pathomorphologic studies. The data obtained allow the conclusion that both elevated and deficient protein content in the diet produces an unfavourable effect on cadmium intoxication. The diet that is balanced according to protein promoted the decrease of the toxic effect of cadmium on the body.
研究了在饮食中蛋白质含量不同的条件下镉对机体产生的影响。对白鼠进行的实验持续了6个月。设有一个对照组和3个实验组，它们食用等热量的半合成饮食，只是蛋白质含量不同。最佳饮食含18%的蛋白质，过量饮食含30%的蛋白质，缺乏饮食含5%的蛋白质。所有实验动物每天随饮食摄入100微克/千克氯化镉，这引发了镉中毒。在实验过程中，对动物的总体健康状况和体重、肾脏、肝脏及精子功能以及镉代谢进行了检查。对肾脏、肝脏和睾丸进行了病理形态学研究。所获数据得出结论：饮食中蛋白质含量过高或过低都会对镉中毒产生不利影响。蛋白质均衡的饮食可促进降低镉对机体的毒性作用。
