下尿路症状与社区居住老年男性跌倒事件:康科德健康与男性衰老研究。

Lower Urinary Tract Symptoms and Incident Falls in Community Dwelling Older Men: The Concord Health and Ageing in Men Project.

机构信息

Centre for Education and Research on Ageing, and Ageing and Alzheimer's Institute, New South Wales, Australia.

Department of Urology, Concord Hospital, University of Sydney, New South Wales, Australia.

出版信息

J Urol. 2016 Dec;196(6):1694-1699. doi: 10.1016/j.juro.2016.06.085. Epub 2016 Jun 24.

Abstract

PURPOSE

We sought to determine which lower urinary tract symptoms are associated with incident falls in community dwelling older men.

MATERIALS AND METHODS

The Concord Health and Ageing in Men Project involves a representative sample of community dwelling men 70 years old or older in a defined geographic region in Sydney, New South Wales, Australia. Included in analysis were 1,090 men without neurological diseases, poor mobility or dementia at baseline. Lower urinary tract symptoms were assessed using I-PSS (International Prostate Symptom Score) and incontinence was assessed using ICIQ (International Consultation on Incontinence Questionnaire) at baseline. I-PSS subscores were calculated for storage and voiding symptoms. Incident falls in 1 year were determined by telephone followup every 4 months.

RESULTS

I-PSS storage and voiding subscores were associated with falls. Urgency incontinence was associated with falls (adjusted incidence rate ratio 2.57, 95% CI 1.54-4.30). In addition, intermediate to high I-PSS storage subscores without urgency incontinence were associated with falls (adjusted incidence rate ratio 1.72, 95% CI 1.24-2.38). Other types of incontinence and urgency alone without urgency incontinence were not associated with falls.

CONCLUSIONS

Lower urinary tract storage and voiding symptoms were associated with falls in community dwelling older men. Of the symptoms of overactive bladder urgency incontinence carried a high risk of falls. Storage symptoms also contributed to the fall risk independently of urgency incontinence. Circumstances of falls among men with lower urinary tract symptoms should be explored to understand how lower urinary tract symptoms increase the fall risk and generate hypotheses regarding potential interventions. Furthermore, trials to treat lower urinary tract symptoms in older men should include falls as an end point.

摘要

目的

我们旨在确定哪些下尿路症状与社区居住的老年男性的跌倒事件有关。

材料与方法

Concord 健康与老龄化男性项目涉及澳大利亚新南威尔士州悉尼一个特定地理区域内 70 岁或以上的社区居住男性的代表性样本。在分析中,包括了 1090 名没有神经疾病、行动不便或痴呆症的基线男性。在下尿路症状方面,使用 I-PSS(国际前列腺症状评分)进行评估,使用 ICIQ(国际尿失禁咨询问卷)评估尿失禁。在基线时计算了 I-PSS 的存储和排尿症状的子评分。通过每 4 个月进行一次电话随访确定 1 年内的跌倒事件。

结果

I-PSS 的存储和排尿子评分与跌倒有关。急迫性尿失禁与跌倒有关(调整后的发病率比 2.57,95%CI 1.54-4.30)。此外,伴有急迫性尿失禁的中间至高 I-PSS 存储子评分与跌倒有关(调整后的发病率比 1.72,95%CI 1.24-2.38)。其他类型的尿失禁和仅急迫性尿失禁而没有急迫性尿失禁与跌倒无关。

结论

社区居住的老年男性的下尿路存储和排尿症状与跌倒有关。在急迫性尿失禁的膀胱过度活动症症状中,急迫性尿失禁具有较高的跌倒风险。存储症状也与没有急迫性尿失禁的跌倒风险独立相关。应该探讨有下尿路症状的男性跌倒的情况,以了解下尿路症状如何增加跌倒风险,并提出关于潜在干预措施的假设。此外,针对老年男性下尿路症状的治疗试验应将跌倒作为终点。

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