真实世界证据：膀胱过度活动症患者跌倒致瘀伤和骨折的风险因素：病历分析。
Real-World Evidence for Risk Factors of Bruises and Fractures from Falls in Patients with Overactive Bladder: A Medical Record Analysis.
机构信息
Department of Urology, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.
Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
出版信息
Int J Clin Pract. 2023 Dec 27;2023:3701823. doi: 10.1155/2023/3701823. eCollection 2023.
AIM
To identify the risk factors for bruises and fractures from falls in patients with overactive bladder (OAB).
METHODS
We evaluated 1136 patients with OAB and aged ≥50 years who visited our hospital. Age, sex, frequency of nocturnal urination, and urinary incontinence type were investigated in the 360 eligible patients. Patients were divided into three groups: those patients without falls (no-fall group), those with fall bruises (bruise group), and those with fall fractures (fracture group). The risk factors for bruises and fractures in patients with OAB were evaluated using the logistic regression analysis. In addition, association between the bruises or fractures from falls and the behavior around urination during the night was investigated.
RESULTS
The multivariate logistic regression analysis showed that female sex (odds ratio (OR) 2.888, = 0.030) and nocturnal urination frequency ≥3 times/night (OR vs. ≤2 times/night, 2.940; = 0.040) were significantly associated with bruises. Nocturnal urination frequency ≥3 times/night (OR vs. ≤2 times/night, 2.835; = 0.026) and urge incontinence (OR 3.415, = 0.016) were significantly associated with fractures. Behavior around urination during the night was significantly associated with fractures ( = 0.009).
CONCLUSION
In the real-world clinical setting, increasing nocturnal urination frequency is a common risk factor for bruises and fractures. Also, female sex and urge incontinence were the risk factors for bruises and fractures, respectively. OAB patients with urge incontinence would especially require aggressive intervention to prevent fractures during night-time voiding.
目的
确定伴有膀胱过度活动症（OAB）的患者因跌倒导致瘀伤和骨折的风险因素。
方法
我们评估了 1136 名年龄≥50 岁且患有 OAB 的患者。在 360 名符合条件的患者中，我们调查了年龄、性别、夜间排尿频率和尿失禁类型。患者被分为三组：无跌倒的患者（无跌倒组）、有跌倒瘀伤的患者（瘀伤组）和有跌倒骨折的患者（骨折组）。使用 logistic 回归分析评估 OAB 患者瘀伤和骨折的风险因素。此外，还调查了夜间排尿时的行为与跌倒导致的瘀伤或骨折之间的关系。
结果
多变量 logistic 回归分析显示，女性（比值比（OR）2.888， = 0.030）和夜间排尿频率≥3 次/夜（与≤2 次/夜相比，OR 2.940； = 0.040）与瘀伤显著相关。夜间排尿频率≥3 次/夜（与≤2 次/夜相比，OR 2.835； = 0.026）和急迫性尿失禁（OR 3.415， = 0.016）与骨折显著相关。夜间排尿时的行为与骨折显著相关（ = 0.009）。
结论
在现实临床环境中，夜间排尿频率增加是瘀伤和骨折的常见危险因素。此外，女性和急迫性尿失禁分别是瘀伤和骨折的危险因素。伴有急迫性尿失禁的 OAB 患者尤其需要积极干预，以防止夜间排尿时发生骨折。
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