Blankfield A
Pleasant View Centre, Melbourne, Australia.
Acta Psychiatr Scand. 1989 Apr;79(4):355-62. doi: 10.1111/j.1600-0447.1989.tb10270.x.
A case note study of 518 alcohol-dependent (DSM-III) inpatients examined their reported past history of prescribed psychotropic drug use patterns between 1973-1985. The subjects were cross-matched for gender, age and admission date and stratified into 3 time periods. The characteristics of psychotropic medication recipients were compared with those patients who reported no use of licit medications. Statistical analysis by logistic regression indicated that there was a significant relationship between the past use of psychotropic drugs with a parental history of excessive alcohol intake, the higher levels of MAST scores and the occurrence of past parasuicide events. Patients in their middle years (35-54) tended to have received significantly less psychotropic drugs than the younger or older age groups. The female (70%) to male (48%) ratio of past psychotropic use was 1.4:1. Gender differences were also noted in the use of antidepressants and illicit substances.
一项对518名酒精依赖(DSM-III)住院患者的病历研究,调查了他们报告的1973年至1985年间使用处方精神药物的既往史。根据性别、年龄和入院日期对受试者进行交叉匹配,并分为3个时间段。将接受精神药物治疗者的特征与那些报告未使用合法药物的患者进行比较。逻辑回归统计分析表明,既往使用精神药物与父母有过量饮酒史、较高的MAST评分以及既往自杀未遂事件的发生之间存在显著关系。中年患者(35至54岁)接受的精神药物明显少于年轻或老年组。既往使用精神药物的女性(70%)与男性(48%)比例为1.4:1。在抗抑郁药和非法物质的使用方面也存在性别差异。