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针刺联合西药治疗脑卒中后轻度认知障碍:一项随机对照试验

[Acupuncture combined with western medication for mild cognitive disorder after stroke: a rando- mized controlled trial].

作者信息

Chen Xiaojun, Fang Jianqiao, Shang Yue, Ma Ruijie, Fang Zhen, Xuan Lihua, Wu Xiang, Bao Yehua, Chen Shunxi

出版信息

Zhongguo Zhen Jiu. 2016 Apr;36(4):337-41.

Abstract

OBJECTIVE

To verify the clinical effect of the penetration acupuncture at the acupoints of governor vessel(GV) and bladder meridian on head for mild cognitive disorder after stroke.

METHODS

One hundred and ten patients were randomly divided into an observation group and a control group, 55 cases in each one. Penetration acupuncture was used at the acupoints of GV and bladder meridian on head in the observation group,namely Wuchu (BL 5) to Chengguang (BL 6) and Tongtian (BL 7) to Luoque (BL 8) bilaterally, and Shenting (GV 24) to Xinhui (GV 22), Qianding (GV 21) to Baihui (GV 20), Houding (GV 19) to Qiangjian (GV 18). Body acupuncture and conventional western medication were applied in the both two groups. Acupuncture was adopted once a day, five times a week and eight weeks totally. The changes of Montreal Cognitive Assessment (MoCA), Mini mental state examination scale(MMSE), self-rating depressive scale (SDS) and activities of daily living scale (Barthel index) were compared between the two groups before treatment, in the middle of treatment(at the forth week) after treatment(at the eighth week) and in three weeks after treatment(follow-up).

RESULTS

After treatment of four and eight weeks and at the time of follow-up, the results of MoCA, MMSE, SDS and Barthel index were apparently im proved compared with those before treatment in the two groups (all P < 0.01). After treatment of eight weeks and at the time of follow-up, the scores of MoCA and SDS were obviously improved in the observation group compared with those in the control group (P < 0.01, P < 0.05). The improvements of MMSE in the observation group were more marked than those in the control group at all times (P < 0.01, P < 0.05). But there was no statistical significance about the change of Barthel index between the two groups (all P > 0.05).

CONCLUSION

Penetration acupuncture at the acupoints of GV and bladder meridian on head can remarkablely improve the cognitive function of the patients with mild cognitive disorder after stroke,and have some efficacy of relieving the bad mood such as depression.

摘要

目的

验证头部督脉与膀胱经透刺法对脑卒中后轻度认知障碍的临床疗效。

方法

将110例患者随机分为观察组和对照组,每组55例。观察组采用头部督脉与膀胱经透刺法,即双侧五处(BL 5)透承光(BL 6)、通天(BL 7)透络却(BL 8),以及神庭(GV 24)透囟会(GV 22)、前顶(GV 21)透百会(GV 20)、后顶(GV 19)透强间(GV 18)。两组均采用体针及常规西药治疗。针刺每日1次,每周5次,共8周。比较两组治疗前、治疗中期(第4周)、治疗后(第8周)及治疗后3周(随访)时蒙特利尔认知评估量表(MoCA)、简易精神状态检查表(MMSE)、自评抑郁量表(SDS)及日常生活活动能力量表(Barthel指数)的变化。

结果

治疗4周、8周及随访时,两组MoCA、MMSE、SDS及Barthel指数结果均较治疗前明显改善(均P<0.01)。治疗8周及随访时,观察组MoCA及SDS评分较对照组明显改善(P<0.01,P<0.05)。观察组MMSE在各时间点的改善均较对照组明显(P<0.01,P<0.05)。但两组Barthel指数变化差异无统计学意义(均P>0.05)。

结论

头部督脉与膀胱经透刺法可显著改善脑卒中后轻度认知障碍患者的认知功能,并具有一定的缓解抑郁等不良情绪的作用。

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