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针刺联合计算机辅助认知训练治疗脑卒中后认知障碍:一项随机对照试验

[ acupuncture combined with computer-assisted cognitive training for post stroke cognitive impairment: a randomized controlled trial].

作者信息

Zheng Chan-Juan, Xia Wen-Guang, Duan Can, Li Zheng-Liang, Li Qing-Lin

机构信息

Rehabilitation Medicine Center of Hubei Hospital of Integrated Chinese and Western Medicine, Wuhan 430015, China.

出版信息

Zhongguo Zhen Jiu. 2021 Mar 12;41(3):247-51. doi: 10.13703/j.0255-2930.20200311-k0001.

DOI:10.13703/j.0255-2930.20200311-k0001
PMID:33798304
Abstract

OBJECTIVE

To explore the effect of acupuncture combined with computer-assisted cognitive training on the recovery of cognitive function and activities of daily living in patients with post stroke cognitive impairment.

METHODS

A total of 98 patients with post stroke cognitive impairment were randomized into an observation group (50 cases, 6 cases dropped off) and a control group (48 cases, 5 cases dropped off). Both groups were treated with conventional treatment, such as computer-assisted cognitive training. On the basis of the conventional treatment, acupuncture at Taixi (KI 3), Sanyinjiao (SP 6), Shuigou (GV 26), Baihui (GV 20), ect. was given in the observation group. In the control group, acupuncture at acupoints of limbs was given. The treatment was given once a day, 5 times a week for 8 weeks. Before and after treatment, the scores of Montreal cognitive assessment (MoCA) scale, modified Barthel index (MBI) and stroke syndrome of TCM scale were used to evaluate the cognitive function, activities of daily living and syndrome of TCM in the two groups. The latency and amplitude of P300 were detected by electromyographs and evoked response instrument. And the clinical efficacy was evaluated in the two groups.

RESULTS

Compared before treatment, the MoCA and MBI scores were increased (<0.01), and the scores of stroke syndrome of TCM scale were decreased (<0.01) after treatment in the two groups. After treatment,the MoCA and MBI scores in the observation group were higher than the control group (<0.01, <0.05), and the score of stroke syndrome of TCM scale was lower than the control group (<0.05). Compared before treatment, the latency of P300 was shortened and amplitude was prolonged after treatment in the two groups (<0.01). After treatment, in the observation group, the latency of P300 was shorter, and amplitude was longer than the control group (<0.01). The effective rate was 86.4% (38/44) in the observation group, which was higher than 67.4% (29/43) in the control group (<0.01).

CONCLUSION

acupuncture combined with computer-assisted cognitive training could improve the cognitive function of patients with post stroke cognitive impairment.

摘要

目的

探讨针刺联合计算机辅助认知训练对脑卒中后认知障碍患者认知功能及日常生活活动能力恢复的影响。

方法

将98例脑卒中后认知障碍患者随机分为观察组(50例,脱落6例)和对照组(48例,脱落5例)。两组均给予常规治疗,如计算机辅助认知训练。观察组在常规治疗基础上,针刺太溪(KI 3)、三阴交(SP 6)、水沟(GV 26)、百会(GV 20)等穴位。对照组针刺四肢穴位。治疗每日1次,每周5次,共8周。治疗前后采用蒙特利尔认知评估(MoCA)量表、改良Barthel指数(MBI)及中医中风证候量表评分评估两组患者的认知功能、日常生活活动能力及中医证候。采用肌电图和诱发电位仪检测P300的潜伏期和波幅。并评估两组的临床疗效。

结果

与治疗前比较,两组治疗后MoCA和MBI评分升高(<0.01),中医中风证候量表评分降低(<0.01)。治疗后,观察组MoCA和MBI评分高于对照组(<0.01,<0.05),中医中风证候量表评分低于对照组(<0.05)。与治疗前比较,两组治疗后P300潜伏期缩短,波幅延长(<0.01)。治疗后,观察组P300潜伏期短于对照组,波幅长于对照组(<0.01)。观察组有效率为86.4%(38/44),高于对照组的67.4%(29/43)(<0.01)。

结论

针刺联合计算机辅助认知训练可改善脑卒中后认知障碍患者的认知功能。

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