Mutsaers E R, Kloppenburg G, Lavrijsen A P M
Leids Universitair Medisch Centrum, Leiden.
Ned Tijdschr Geneeskd. 2016;160:A9980.
A 69-year-old man with rheumatoid arthritis developed a discoid rash on his face years after the initiation of treatment with adalimumab. Serological tests were positive for antinuclear antibodies (ANA) and autoantibodies against Sjögren's syndrome-related antigen A (SSA). We diagnosed him with 'lupus-like syndrome'. After discontinuation of the adalimumab therapy and the use of topical corticosteroids, his symptoms resolved quickly.
一名69岁的类风湿性关节炎患者在开始使用阿达木单抗治疗数年后，面部出现了盘状皮疹。血清学检查显示抗核抗体（ANA）和抗干燥综合征相关抗原A（SSA）自身抗体呈阳性。我们诊断他患有“狼疮样综合征”。停用阿达木单抗治疗并使用外用皮质类固醇后，他的症状迅速缓解。
