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毛发修复手术的实验证据:拔毛后的存活及生长速率

Experimental Evidence in Hair Restoration Procedures: Plucked Hair Survival and Growth Rate.

作者信息

Raposio Edoardo, Caruana Giorgia

机构信息

Department of Surgical Sciences, Plastic Surgery Unit, University of Parma, and Cutaneous, Mini-invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy.

出版信息

J Clin Aesthet Dermatol. 2016 Mar;9(3):39-41. Epub 2016 Mar 1.

PMID:27354887
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4896820/
Abstract

BACKGROUND

Limitations of hair restoration procedures are the amount of hairs available and the invasiveness of follicular harvesting.

OBJECTIVE

The aim of this study was to compare conventional human micrografts and plucked hair follicles in an in vitro model in order to test hair growth rates for experimentally assessing the soundness of plucked follicle use in hair transplantation procedures.

METHODS AND MATERIALS

A total of 100 conventional one-hair micrografts (group A; control) and a total of 80 plucked hair follicles (group B; experimental) were obtained from 14 healthy male patients. The length of each graft was measured immediately following isolation and at the end of the 10-day culture period. The Kruskal-Wallis one-way analysis of variance by ranks test was used in order to statistically analyze the data obtained.

RESULTS

A statistically significant difference was found between the growth rate of micrografts in control (mean 10-day shaft growth rate = 0.30mm) and experimental (mean 10-day shaft growth rate = 0.36mm) groups.

CONCLUSION

The obtained data shows a higher plucked hair follicle growth rate compared to one-hair micrografts, which leads us to believe that plucked micrografts could be a useful and less invasive adjunct in the field of hair transplantation surgery.

摘要

背景

毛发移植手术的局限性在于可用毛发数量以及毛囊采集的侵入性。

目的

本研究的目的是在体外模型中比较传统的人类微小移植物和拔取的毛囊,以测试毛发生长率,从而通过实验评估在毛发移植手术中使用拔取毛囊的合理性。

方法和材料

从14名健康男性患者身上获取了总共100个传统的单根毛发微小移植物(A组;对照组)和总共80个拔取的毛囊(B组;实验组)。每个移植物的长度在分离后立即测量,并在10天培养期结束时测量。使用Kruskal-Wallis秩和检验进行单因素方差分析,以便对获得的数据进行统计分析。

结果

在对照组(平均10天毛干生长率 = 0.30毫米)和实验组(平均10天毛干生长率 = 0.36毫米)的微小移植物生长率之间发现了统计学上的显著差异。

结论

获得的数据表明,与单根毛发微小移植物相比,拔取的毛囊生长率更高,这使我们相信拔取的微小移植物可能是毛发移植手术领域中一种有用且侵入性较小的辅助手段。

相似文献

1
Experimental Evidence in Hair Restoration Procedures: Plucked Hair Survival and Growth Rate.毛发修复手术的实验证据:拔毛后的存活及生长速率
J Clin Aesthet Dermatol. 2016 Mar;9(3):39-41. Epub 2016 Mar 1.
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本文引用的文献

1
Scalp Surgery: Quantitative Analysis of Follicular Unit Growth.头皮手术:毛囊单位生长的定量分析
Plast Reconstr Surg Glob Open. 2015 Oct 20;3(10):e539. doi: 10.1097/GOX.0000000000000524. eCollection 2015 Oct.
2
Eyebrow reconstruction by punch hair transplantation.眉再造术采用打孔移植头发。
Plast Reconstr Surg. 1977 Jul;60(1):74-6. doi: 10.1097/00006534-197707000-00010.
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Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells.从皮肤或拔出的头发中分离和培养人角质形成细胞,用于生成诱导多能干细胞。
Nat Protoc. 2010 Feb;5(2):371-82. doi: 10.1038/nprot.2009.241. Epub 2010 Feb 4.
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Characterization of multipotent cells from human adult hair follicles.成人人类毛囊多能细胞的特性分析。
Toxicol In Vitro. 2007 Mar;21(2):320-3. doi: 10.1016/j.tiv.2006.07.017. Epub 2006 Aug 25.
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Eyebrow reconstruction following burn injury.烧伤后眉毛重建。
Burns. 2005 Jun;31(4):495-9. doi: 10.1016/j.burns.2004.10.021. Epub 2005 Mar 2.
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Location and phenotype of human adult keratinocyte stem cells of the skin.人类皮肤成人角质形成干细胞的位置与表型
Differentiation. 2004 Oct;72(8):387-95. doi: 10.1111/j.1432-0436.2004.07208005.x.
7
Human follicular stem cells: their presence in plucked hair and follicular cell culture.人毛囊干细胞:其在拔下毛发及毛囊细胞培养物中的存在情况。
Br J Dermatol. 2004 May;150(5):860-8. doi: 10.1111/j.1365-2133.2004.05862.x.
8
Follicular unit extraction: minimally invasive surgery for hair transplantation.毛囊单位提取术:毛发移植的微创手术
Dermatol Surg. 2002 Aug;28(8):720-8. doi: 10.1046/j.1524-4725.2002.01320.x.
9
Effects of cooling micrografts in hair transplantation surgery.毛发移植手术中冷却微移植体的效果。
Dermatol Surg. 1999 Sep;25(9):705-7. doi: 10.1046/j.1524-4725.1999.98287.x.
10
The use of micrografts and minigrafts for the treatment of burn alopecia.使用微小移植物和迷你移植物治疗烧伤后脱发。
Plast Reconstr Surg. 1999 Feb;103(2):581-4. doi: 10.1097/00006534-199902000-00034.