Raposio Edoardo, Caruana Giorgia
Department of Surgical Sciences, Plastic Surgery Unit, University of Parma, and Cutaneous, Mini-invasive, Regenerative and Plastic Surgery Unit, Parma University Hospital, Parma, Italy.
J Clin Aesthet Dermatol. 2016 Mar;9(3):39-41. Epub 2016 Mar 1.
Limitations of hair restoration procedures are the amount of hairs available and the invasiveness of follicular harvesting.
The aim of this study was to compare conventional human micrografts and plucked hair follicles in an in vitro model in order to test hair growth rates for experimentally assessing the soundness of plucked follicle use in hair transplantation procedures.
A total of 100 conventional one-hair micrografts (group A; control) and a total of 80 plucked hair follicles (group B; experimental) were obtained from 14 healthy male patients. The length of each graft was measured immediately following isolation and at the end of the 10-day culture period. The Kruskal-Wallis one-way analysis of variance by ranks test was used in order to statistically analyze the data obtained.
A statistically significant difference was found between the growth rate of micrografts in control (mean 10-day shaft growth rate = 0.30mm) and experimental (mean 10-day shaft growth rate = 0.36mm) groups.
The obtained data shows a higher plucked hair follicle growth rate compared to one-hair micrografts, which leads us to believe that plucked micrografts could be a useful and less invasive adjunct in the field of hair transplantation surgery.
毛发移植手术的局限性在于可用毛发数量以及毛囊采集的侵入性。
本研究的目的是在体外模型中比较传统的人类微小移植物和拔取的毛囊,以测试毛发生长率,从而通过实验评估在毛发移植手术中使用拔取毛囊的合理性。
从14名健康男性患者身上获取了总共100个传统的单根毛发微小移植物(A组;对照组)和总共80个拔取的毛囊(B组;实验组)。每个移植物的长度在分离后立即测量,并在10天培养期结束时测量。使用Kruskal-Wallis秩和检验进行单因素方差分析,以便对获得的数据进行统计分析。
在对照组(平均10天毛干生长率 = 0.30毫米)和实验组(平均10天毛干生长率 = 0.36毫米)的微小移植物生长率之间发现了统计学上的显著差异。
获得的数据表明,与单根毛发微小移植物相比,拔取的毛囊生长率更高,这使我们相信拔取的微小移植物可能是毛发移植手术领域中一种有用且侵入性较小的辅助手段。