Srebro Z, Szirmai E
Agressologie. 1989 Feb;30(2):85-8.
Three days following bilateral adrenalectomy the following findings were revealed in the hypothalamus-hypophysis and circum-ventricular organs of Balb mice: considerable enlargement of neuronal perikarya and nuclei in the nucleus arcuatus of the hypothalamus. Amitotic divisions were frequent in neurons and glial cells. Mitoses were also sporadically encountered. The pars distalis of the hypophysis showed typical post-adrenalectomy changes. In addition, enlargement of the so-called pars rostralis was observed. This part and the pars intermedia showed signs of enhanced secretion. The subfornical organ of the adrenalectomized animals was much smaller than in the controls. The subcommissural organ and pineal gland, on the contrary, were large and apparently actively secreting.
双侧肾上腺切除术后三天，在Balb小鼠的下丘脑 - 垂体及室周器官中发现以下情况：下丘脑弓状核内神经元胞体和细胞核显著增大。神经元和神经胶质细胞中无丝分裂频繁，也偶尔可见有丝分裂。垂体远侧部呈现典型的肾上腺切除术后变化。此外，观察到所谓的嘴侧部增大，该部分和中间部显示出分泌增强的迹象。肾上腺切除动物的穹窿下器官比对照组小得多。相反，连合下器官和松果体则较大且明显在积极分泌。
