Al-Qarni Ahmed, Lewington Matthew R, Wong Ivan H
Dalhousie University and the Division of Orthopaedic Surgery, Capital District Health Authority, Halifax, Nova Scotia, Canada.
Arthrosc Tech. 2016 Mar 14;5(2):e257-62. doi: 10.1016/j.eats.2015.12.005. eCollection 2016 Apr.
It is well known that articular cartilage defects have little capability to heal. For grade III or IV cartilage defects, surgical intervention may be required for symptomatic patients. Microfracture is a commonly used surgical technique to address these injuries. However, microfracture has drawbacks, which include the risk of ossification of the newly formed tissue, as well as the imperfect and fragile nature of the fibrous cartilage. Given the challenges associated with microfracture, BST-CarGel (Piramal Healthcare, Laval, Quebec, Canada) has been developed to stabilize and support the nascent clot. This chitin-based polymer is mixed with the patient's own blood and inserted onto the microfractured defect. The polymer allows normal clot formation and provides a matrix to strengthen the clot, prevent retraction, and increase its adhesiveness to the natural tissue. We present, with a video example, a detailed arthroscopic technique for using BST-CarGel to fill a focal femoral head cartilage defect.
众所周知，关节软骨缺损的自愈能力很差。对于III级或IV级软骨缺损，有症状的患者可能需要手术干预。微骨折是治疗这些损伤常用的外科技术。然而，微骨折存在缺点，包括新形成组织骨化的风险，以及纤维软骨不完美和脆弱的特性。鉴于微骨折存在的挑战，已研发出BST-CarGel（加拿大魁北克省拉瓦尔市派拉蒙医疗保健公司）来稳定和支撑新生的凝块。这种基于几丁质的聚合物与患者自身血液混合后，植入微骨折缺损处。该聚合物可使正常凝块形成，并提供一个基质来强化凝块、防止凝块回缩，并增加其与天然组织的黏附性。我们通过一个视频示例展示了使用BST-CarGel填充股骨头局灶性软骨缺损的详细关节镜技术。
