Bunnag C, Dhorranintra B, Limsuvan S, Jareoncharsri P
Department of Pharmacology, Faculty of Medicine and Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Ann Allergy. 1989 Jun;62(6):554-8.
In our recent survey, fern spores were found to be the third most common airborne air spora in the Bangkok atmosphere; therefore, the significance of fern spores as a causative allergen was assessed in patients with allergic rhinitis. By using the extract from the spores of Acrostichum aureum Linn, which is a widespread fern, an intracutaneous test was done in 226 allergic rhinitis patients and 61.5% of these patients reacted positively. Nasal provocation test by using the same kind of fern spore extract was also performed in 24 allergic rhinitis patients and the positive reaction occurred in 70.8%. When skin tests and nasal provocation tests were performed in a group of 20 nonallergic ENT patients, only 20% gave weakly positive skin test reactions and 15% gave mild reactions to the nasal provocation test. The authors concluded that fern spores are potentially allergenic and allergists should be aware that ferns could be an important aeroallergen.
在我们最近的调查中，发现蕨类孢子是曼谷大气中第三常见的空气传播孢子；因此，对过敏性鼻炎患者评估了蕨类孢子作为致敏变应原的重要性。通过使用一种广泛分布的蕨类植物——金毛狗蕨的孢子提取物，对226名过敏性鼻炎患者进行了皮内试验，其中61.5%的患者反应呈阳性。还对24名过敏性鼻炎患者使用同一种蕨类孢子提取物进行了鼻激发试验，阳性反应发生率为70.8%。当对一组20名非过敏性耳鼻喉科患者进行皮肤试验和鼻激发试验时，只有20%的患者皮试反应呈弱阳性，15%的患者对鼻激发试验有轻度反应。作者得出结论，蕨类孢子具有潜在的致敏性，过敏症专科医生应意识到蕨类可能是一种重要的空气变应原。
