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[通过琼脂扩散法测定细菌对抗生素的敏感性及使用API ATB系统:一项比较研究]

[Determination of the sensitivity of bacteria to antibiotics by an agar diffusion method and use of the API ATB system: a comparative study].

作者信息

Reynaud A E, Coude du Foresto B, Courtieu A L

机构信息

Laboratoire de Bactériologie A, Nantes.

出版信息

Ann Biol Clin (Paris). 1989;47(2):71-5.

PMID:2735566
Abstract

130 bacterial strains were studied for their antibiotics sensitivity by an agar diffusion method and using API ATB System: 50 Enterobacteriaceae, 12 other Gram negative bacilli, 48 Staphylococci and 20 Streptococci. The results concurred in 83 p. cent of the cases. Discrepancies were essentially observed for coagulase negative Staphylococci and Streptococci. Strains appeared more resistant by API ATB System than by the agar diffusion method. Discrepancies mostly concerned beta-lactam antibiotic sensitivity for Gram negative bacilli or aminoglycosides and macrolides sensitivity for Staphylococci. They also concerned sulfamides and trimethoprim sensitivity for all bacterial species.

摘要

采用琼脂扩散法并使用API ATB系统对130株细菌进行了抗生素敏感性研究,其中包括50株肠杆菌科细菌、12株其他革兰氏阴性杆菌、48株葡萄球菌和20株链球菌。结果在83%的病例中一致。差异主要出现在凝固酶阴性葡萄球菌和链球菌中。通过API ATB系统检测的菌株比通过琼脂扩散法检测的菌株表现出更高的耐药性。差异主要涉及革兰氏阴性杆菌对β-内酰胺类抗生素的敏感性,或葡萄球菌对氨基糖苷类和大环内酯类抗生素的敏感性。差异还涉及所有细菌种类对磺胺类药物和甲氧苄啶的敏感性。

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