生理学：压力下的染色质可促进长寿。
Physiology: Stressed-out chromatin promotes longevity.
作者信息
Lee Siu Sylvia, Tyler Jessica K
机构信息
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14850, USA.
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York 10065, USA.
出版信息
Nature. 2016 Jun 30;534(7609):625-6. doi: 10.1038/534625a.
Abstract
Two studies reveal that early-life malfunction in organelles called mitochondria brings about lasting changes in how DNA is packaged. These alterations have consequences for cellular stress responses and organismal longevity.
摘要
两项研究表明，称为线粒体的细胞器在生命早期出现的功能异常会导致DNA包装方式发生持久变化。这些改变会对细胞应激反应和生物体寿命产生影响。
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