Colavita L, Cuppari C, Pizzino M R, Sturiale M, Mondello B, Monaco F, Barone M, Salpietro C
Department of Genetics and Paediatric Immunology, University Hospital of Messina, Messina, Italy.
Unit of Thoracic Surgery, Department of Cardiovascular and Thoracic Sciences, University Hospital of Messina, Messina, Italy.
J Biol Regul Homeost Agents. 2016 Apr-Jun;30(2):585-8.
Pneumomediastinum (PM), subcutaneous emphysema (SE) and pneumorrhachis (also known as epidural air (EDA) or epidural emphysema) are very rare findings in children. PM is defined as the passage of air from intra-alveolar space to interstitium and, later, to the mediastinum. From the mediastinum, the air may catch up subcutaneous tissue (usually of the neck) and/or epidural space via the cervical fascial planes and neural foramina, forming respectively SE and EDA. The PM can be divided in spontaneous (or idiopathic) and secondary PM. Only few studies have evaluated the exact incidence of PM and its complications in children, and to define the correct diagnostic work up, treatment and outpatient follow-up. We report the case of a 9-year-old child with undiagnosed asthma that, during severe asthmatic flare secondary to acute infection of high airway, developed PM, SE and EDA.
纵隔气肿(PM)、皮下气肿(SE)和脊髓积气(也称为硬膜外积气(EDA)或硬膜外气肿)在儿童中是非常罕见的表现。纵隔气肿定义为空气从肺泡内间隙进入间质,随后进入纵隔。空气从纵隔可通过颈部筋膜平面和神经孔进入皮下组织(通常是颈部)和/或硬膜外间隙,分别形成皮下气肿和硬膜外积气。纵隔气肿可分为自发性(或特发性)纵隔气肿和继发性纵隔气肿。仅有少数研究评估了儿童纵隔气肿的确切发病率及其并发症,并确定正确的诊断检查、治疗和门诊随访方案。我们报告了一例9岁未确诊哮喘患儿的病例,该患儿在因上呼吸道急性感染继发严重哮喘发作期间,出现了纵隔气肿、皮下气肿和脊髓积气。