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心脏手术后房颤患者使用非维生素K口服抗凝剂:欧洲心律协会调查结果

Non-vitamin K oral anticoagulants in patients with atrial fibrillation after cardiac surgery: the results of the European Heart Rhythm Association Survey.

作者信息

Vranckx Pascal, Potpara Tatjana, Dagres Nikolaos, Heidbuchel Hein

机构信息

Heart Center Hasselt, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium.

School of Medicine, Belgrade University, Belgrade, Serbia Cardiology Clinic, Clinical Centre of Serbia, Belgrade, Serbia.

出版信息

Europace. 2016 Jul;18(7):1113-6. doi: 10.1093/europace/euw208.

Abstract

The purpose of this European Heart Rhythm Association survey was to assess the current practice concerning the use of oral anticoagulation in patients with post-operative atrial fibrillation (pre-existing or new-onset). The survey highlights the considerable heterogeneity of the type of anticoagulation, with 25% of the centres never using the non-vitamin K antagonist oral anticoagulants (NOACs) in this setting, as well the timing of oral anticoagulation initiation, the use and dosing of low-molecular-weight heparins, and the duration of anticoagulation when sinus rhythm is restored. One-third of the centres stated that they perceived that the risk of major pericardial bleeding requiring pericardiocentesis was higher when NOACs were used compared with vitamin K antagonists. Overall, the responding centres estimated the incidence of major pericardial haemorrhage to be 2.4%. More data are needed to inform practice guidelines in this field.

摘要

欧洲心律协会此次调查的目的是评估目前针对术后房颤(既往存在或新发)患者使用口服抗凝药的实际情况。该调查突出了抗凝类型存在的显著异质性,25%的中心在这种情况下从未使用过非维生素K拮抗剂口服抗凝药(NOACs),同时还包括口服抗凝药起始时间、低分子量肝素的使用和剂量,以及恢复窦性心律时抗凝持续时间。三分之一的中心表示,他们认为与维生素K拮抗剂相比,使用NOACs时发生需要心包穿刺的严重心包出血风险更高。总体而言,回复调查的中心估计严重心包出血的发生率为2.4%。该领域需要更多数据来为实践指南提供依据。

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