Takata Nozomu, Eiraku Mototsugu, Sakakura Eriko
Laboratory for in vitro Histogenesis, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan; Center for Vascular and Developmental Biology, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 East Superior Street, Chicago 60611, IL, USA.
Laboratory for in vitro Histogenesis, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.
Data Brief. 2016 Jun 3;8:465-9. doi: 10.1016/j.dib.2016.05.070. eCollection 2016 Sep.
This article contains data related to the research article entitled "Specification of embryonic stem cell-derived tissues into eye fields by Wnt signaling using rostral diencephalic tissue-inducing culture" Sakakura (2016) [1]. Mouse embryonic stem cells (ESC) were used for the generation of optic vesicle-like tissues in vitro. In this article we described data in which a Rax::GFP knock-in ESC line was used to monitor the formation of optic tissues. In addition, we also described the data of regional marker expression of Rax, Sox2 and Pax6 in vivo around the forebrain and the eye tissues for comparative purposes. These data can be valuable to researchers interested in investigating forebrain and eye tissue development.
本文包含与研究论文相关的数据，该研究论文题为《利用头侧间脑组织诱导培养通过Wnt信号通路将胚胎干细胞衍生组织定向分化为眼区》，作者坂仓（2016年）[1]。小鼠胚胎干细胞（ESC）被用于体外生成类视泡组织。在本文中，我们描述了使用Rax::GFP基因敲入ESC系来监测视组织形成的数据。此外，为了进行比较，我们还描述了体内前脑和眼组织周围Rax、Sox2和Pax6区域标记物表达的数据。这些数据对于有兴趣研究前脑和眼组织发育的研究人员可能有价值。
