Leventhal L J, Kuritsky L, Ginsburg R, Bomalaski J S
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104.
Am J Emerg Med. 1989 Jul;7(4):409-10. doi: 10.1016/0735-6757(89)90049-1.
A 42-year-old woman was hospitalized with aspirin intoxication. The patient developed massive skeletal muscle damage without any evidence of muscle compression, hyperthermia, or other predisposing factors. The exact mechanism by which salicylates cause muscle damage is unknown, but the muscle damage appears to be the result of a direct toxic effect. This represents the first case of isolated salicylate-induced rhabdomyolysis.
一名42岁女性因阿司匹林中毒入院。该患者出现了大面积骨骼肌损伤,没有任何肌肉受压、体温过高或其他诱发因素的证据。水杨酸盐导致肌肉损伤的确切机制尚不清楚,但肌肉损伤似乎是直接毒性作用的结果。这是首例孤立性水杨酸盐诱导的横纹肌溶解症病例。