慢性阻塞性肺疾病（COPD）和囊性纤维化患者六分钟步行试验期间步态速度的变异性。
Variability of gait speed during six minutes walking test in COPD and cystic fibrosis patients.
作者信息
Reychler Gregory, Debatisse Margaux, Lebecque Patrick, Pieters Thierry, Liistro Giuseppe, Gohy Sophie
机构信息
Service de Pneumologie, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; Institut de Recherche Expérimentale et Clinique (IREC), Pôle de Pneumologie, ORL & Dermatologie, Université Catholique de Louvain, 1200 Brussels, Belgium; Service de Médecine Physique et Réadaptation, Cliniques universitaires Saint-Luc, 1200 Brussels, Belgium; Parnasse-ISEI, Haute Ecole Leonard de Vinci, 1200 Brussels, Belgium.
Parnasse-ISEI, Haute Ecole Leonard de Vinci, 1200 Brussels, Belgium.
出版信息
Gait Posture. 2016 Sep;49:36-40. doi: 10.1016/j.gaitpost.2016.06.007. Epub 2016 Jun 8.
BACKGROUND
Recently, gait speed reached an increasing importance in the management of respiratory patients. The aim of this retrospective study was to compare walking speed and physiological adaptations during the 6MWT in COPD and CF patients.
METHODS
6MWT performed by COPD and CF patients were retrospectively reviewed. Global and sequential walking speeds were measured on six minutes and every sequence of two minutes respectively. Heart rate, oxygen saturation and dyspnea were analyzed.
RESULTS
78 and 246 tests from CF and COPD patients were reviewed respectively. FEV1 (52.3 vs 56.2% pred) and FVC (72.5 vs 73.8% pred) were similar between both diseases. However, 6MWT in patients with CF were characterized by significantly higher heart rate, global walking speed and walking distance (+68%) while dyspnea evolutions and the proportions of patients presenting walking speed decline over the 6min were significantly lower.
CONCLUSION
Walking speed and cardio-respiratory parameters evolution during 6MWT differ between COPD and CF patients.
背景
近年来，步速在呼吸系统疾病患者的管理中变得越来越重要。这项回顾性研究的目的是比较慢性阻塞性肺疾病（COPD）和囊性纤维化（CF）患者在6分钟步行试验（6MWT）中的步行速度和生理适应性。
方法
对COPD和CF患者进行的6MWT进行回顾性分析。分别在6分钟和每2分钟的时间段测量整体和阶段性步行速度。分析心率、血氧饱和度和呼吸困难情况。
结果
分别回顾了CF和COPD患者的78次和246次测试。两种疾病患者的第一秒用力呼气容积（FEV1）（预计值的52.3%对56.2%）和用力肺活量（FVC）（预计值的72.5%对73.8%）相似。然而，CF患者的6MWT表现为心率显著更高、整体步行速度和步行距离显著增加（+68%），而呼吸困难的变化以及在6分钟内步行速度下降的患者比例显著更低。
结论
COPD和CF患者在6MWT期间的步行速度和心肺参数变化有所不同。
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