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下肢无瓣膜深静脉患者股总静脉单尖瓣形成的长期结果。

Long-term results of the monocusp valve formation in the common femoral vein in patients with avalvular deep veins of the lower extremities.

作者信息

Ignatyev Igor M, Akhmetzyanov Rustem V

机构信息

Department of Vascular Surgery, Interregional Clinical and Diagnostic Center, Course of Cardiovascular Surgery, Russian State Medical University, Kazan, Russia -

Department of Vascular Surgery, Interregional Clinical and Diagnostic Center, Course of Cardiovascular Surgery, Russian State Medical University, Kazan, Russia.

出版信息

Int Angiol. 2017 Apr;36(2):116-121. doi: 10.23736/S0392-9590.16.03638-5. Epub 2016 Jun 30.

Abstract

BACKGROUND

Aim of the study was to evaluate the long-term results of the monocusp valve formation in the common femoral vein (CFV) in patients with avalvular deep veins (ADV) of the lower extremities.

METHODS

A total of 36 patients (24 women and 12 men) at the age varying from 37 to 58 years old were given surgical treatment during the period from 2008 to 2014. Six patients presented with congenital ADV, while the remaining 30 ADV had a consequence of the post-thrombotic lesion in the valves with the complete recanalization and manifested deep venous axial reflux. In terms of CEAP clinical classification, the patients were categorized into the following groups: С4b (N.=11), C5 (N.=18), C6 (N.=7). All the patients underwent Duplex ultrasound (DUS) examination. Twelve patients were additionally examined by venography. Kistner grade IV reflux was diagnosed in all the patients. Twenty-eight patients had undergone surgical interventions on superficial and perforating veins before. The severe (C4b-C6) forms of chronic venous disease with manifested axial reflux in deep veins were regarded as an indication for surgery in the patients refractory to traditional treatment. The method described by Opie et al. was employed to construct the monocusp venous valve in the CFV.

RESULTS

The long-term results of the treatment were evaluated in 26 patients followed up during the period from 18 to 48 (mean 29.5±8.2) months. Cumulative clinical success rate at four years was 76.5%. Freedom from ulcer recurrence at four years was 83.4% (C6 patients). Cumulative competence rate of the neovalve was accomplished in 70.6%. The evaluation in two years based on the VCSS revealed the reduction in the severity of the manifestations of chronic venous insufficiency (P<0.01). The quality of life was improved, its index decreased from 60.6±18.7 to 40.7±12.8 (P<0.05). The circumference of the narrowest segment of the tibia decreased from 271.1±4.7 to 256.8±5.7 mm (P<0.05).

CONCLUSIONS

Formation of the monocusp valve in CFV makes it possible to eliminate pathological blood reflux from the inferior vena cava to deep veins of the lower extremities that is known to be one of the main factors in the appearance and progression of chronic venous insufficiency (CVI). The high effectiveness of this operation is confirmed by the well apparent clinical improvement in the state of the affected lower extremity and the quality of life of the patients.

摘要

背景

本研究旨在评估下肢无瓣膜深静脉(ADV)患者股总静脉(CFV)单尖瓣形成的长期效果。

方法

2008年至2014年期间,共36例患者(24例女性和12例男性)接受了手术治疗,年龄在37至58岁之间。6例患者为先天性ADV,其余30例ADV是瓣膜血栓形成后病变导致完全再通并表现为深静脉轴向反流。根据CEAP临床分类,患者分为以下几组:C4b(n = 11)、C5(n = 18)、C6(n = 7)。所有患者均接受了双功超声(DUS)检查。12例患者还接受了静脉造影检查。所有患者均诊断为Kistner IV级反流。28例患者此前接受过浅静脉和穿支静脉手术。对于传统治疗无效的患者,伴有深静脉明显轴向反流的严重(C4b - C6)慢性静脉疾病形式被视为手术指征。采用Opie等人描述的方法在CFV中构建单尖瓣静脉瓣膜。

结果

对26例患者进行了随访,随访时间为18至48(平均29.5±8.2)个月,评估了治疗的长期效果。四年的累积临床成功率为76.5%。四年内溃疡无复发率为83.4%(C6患者)。新瓣膜的累积功能完成率为70.6%。基于VCSS的两年评估显示慢性静脉功能不全表现的严重程度有所降低(P<0.01)。生活质量得到改善,其指数从60.6±18.7降至40.7±12.8(P<0.05)。胫骨最窄段周长从271.1±4.7降至256.8±5.7 mm(P<0.05)。

结论

CFV中单尖瓣的形成使得消除从下腔静脉到下肢深静脉的病理性血液反流成为可能,而这种反流是慢性静脉功能不全(CVI)发生和进展中的主要因素之一。受影响下肢状况和患者生活质量的明显临床改善证实了该手术的高效性。

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