Gould Paul R, Stewart Colin J R, Papadimitriou John M
Department of Histopathology, King Edward Memorial Hospital (P.R.G., C.J.R.S.)Schools of Women's and Infants' Health (C.J.R.S.)Pathology and Laboratory Medicine (J.M.P.), University of Western Australia, Perth, Western Australia.
Int J Gynecol Pathol. 2017 Jan;36(1):90-94. doi: 10.1097/PGP.0000000000000308.
Minimal-deviation endometrioid adenocarcinoma (MDEA) of the uterine cervix is a rare tumor that may be confused histologically with a number of benign lesions as well as other types of endocervical neoplasia. The histologic and immunohistochemical features of MDEA have been described in case reports and in small series, but correlation of these findings with ultrastructural examination has not been documented. Herein we report a 51-yr-old patient who underwent hysterectomy for menorrhagia and was found to have a clinically unsuspected, stage IB cervical MDEA. The light microscopic, immunohistochemical, and electron microscopic features of the tumor are described, with the most significant ultrastructural abnormality being the presence of abnormal cilia and ciliogenesis.
子宫颈微小偏离型子宫内膜样腺癌（MDEA）是一种罕见肿瘤，在组织学上可能会与多种良性病变以及其他类型的子宫颈肿瘤相混淆。MDEA的组织学和免疫组化特征已在病例报告和小系列研究中有所描述，但这些发现与超微结构检查的相关性尚未见文献记载。在此，我们报告一名51岁因月经过多接受子宫切除术的患者，术中发现患有临床未怀疑的IB期子宫颈MDEA。描述了该肿瘤的光镜、免疫组化和电镜特征，最显著的超微结构异常是存在异常纤毛和纤毛发生。
