Mikaelian N P, Stupin I V, Sleta I V
Biull Eksp Biol Med. 1989 May;107(5):604-7.
The first week after the cryodestruction, the resection of plasma flow and combined effect of the two methods causes metabolic changes, which later according to observations are normalized. The metabolic disturbances, which are connected with experimental liver cirrhosis under the combined cryodestructive effect and plasma flow resection are normalized three weeks after treatment. But there is no elimination of defects of free radical oxidation and there remains a decreased insulin binding capability of lymphocytes. All these processes should be taken into account in surgical treatment of liver cirrhosis.
冷冻破坏后的第一周，血浆流量的切除以及两种方法的联合作用会引起代谢变化，根据观察，这些变化随后会恢复正常。在联合冷冻破坏作用和血浆流量切除的情况下，与实验性肝硬化相关的代谢紊乱在治疗三周后恢复正常。但是自由基氧化缺陷并未消除，淋巴细胞的胰岛素结合能力仍然下降。在肝硬化的手术治疗中应考虑到所有这些过程。
