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活体肝移植所需的技术技能。

Technical Skills Required in Split Liver Transplantation.

作者信息

Liu Huanqiu, Li Ruijun, Fu Jinling, He Qianyan, Li Ji

机构信息

Department of Anesthesiology, The First Hospital of Jilin University, Changchun, Jilin, China (mainland).

Department of Hand surgery, The First Hospital of Jilin University, Changchun, Jilin, China (mainland).

出版信息

Ann Transplant. 2016 Jul 1;21:408-15. doi: 10.12659/aot.896351.

Abstract

The number of liver grafts obtained from a cadaver can be greatly increased with the application of split liver transplantation. In the last 10 years, pediatric waiting list mortality has been reduced significantly with the use of this form of liver transplantation, which has 2 major forms. In its most commonly used form, the liver can be transplanted into 1 adult and 1 child by splitting it into a right extended and a left lateral graft. For adult and pediatric recipients, the results of this procedure are comparable to those of whole-organ techniques. In another form, 2 hemi-grafts are obtained by splitting the liver, which can be transplanted into a medium-sized adult (the right side) and a large child/small adult (the left side). The adult liver graft pool is expanded through the process of full right/full left splitting; but it is also a critical technique when one considers the knowledge required of the potential anatomic variations and the high technical skill level needed. In this review, we provide some basic insights into the technical and anatomical aspects of these 2 forms of split liver transplantation and present an updated summary of both forms.

摘要

采用劈离式肝移植可大幅增加从尸体获取的肝移植供体数量。在过去10年中,这种肝移植形式的应用显著降低了儿童等待名单上的死亡率,它有两种主要形式。在其最常用的形式中,肝脏可通过劈分成一个右扩展 graft 和一个左外侧 graft 分别移植给1名成人和1名儿童。对于成人和儿童受者,该手术的结果与全器官技术的结果相当。在另一种形式中,通过劈开肝脏获得2个半肝 graft,可分别移植给一名中等体型的成人(右侧)和一名大龄儿童/小体型成人(左侧)。通过全右/全左劈分过程扩大了成人肝移植供体库;但考虑到潜在的解剖变异所需的知识以及所需的高技术水平,这也是一项关键技术。在本综述中,我们对这两种劈离式肝移植的技术和解剖方面提供了一些基本见解,并对这两种形式进行了最新总结。

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