使用多种测序技术构建蝙蝠白鼻综合征病原体——毁灭拟裸球壳菌的高质量基因组
Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome.
作者信息
Drees Kevin P, Palmer Jonathan M, Sebra Robert, Lorch Jeffrey M, Chen Cynthia, Wu Cheng-Cang, Bok Jin Woo, Keller Nancy P, Blehert David S, Cuomo Christina A, Lindner Daniel L, Foster Jeffrey T
机构信息
Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, New Hampshire, USA.
Center for Forest Mycology Research, Northern Research Station, U.S. Forest Service, Madison, Wisconsin, USA.
出版信息
Genome Announc. 2016 Jun 30;4(3):e00445-16. doi: 10.1128/genomeA.00445-16.
Abstract
White-nose syndrome has recently emerged as one of the most devastating wildlife diseases recorded, causing widespread mortality in numerous bat species throughout eastern North America. Here, we present an improved reference genome of the fungal pathogen Pseudogymnoascus destructans for use in comparative genomic studies.
摘要
白鼻综合征最近已成为有记录以来最具毁灭性的野生动物疾病之一，在北美东部的众多蝙蝠物种中造成了广泛的死亡。在此，我们提供了一种用于比较基因组研究的真菌病原体——毁灭假裸囊菌的改进参考基因组。
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2
Widespread Bat White-Nose Syndrome Fungus, Northeastern China.中国东北地区广泛存在的蝙蝠白鼻综合征真菌。
Emerg Infect Dis. 2016 Jan;22(1):140-2. doi: 10.3201/eid2201.151314.
3
Fungal artificial chromosomes for mining of the fungal secondary metabolome.用于挖掘真菌次级代谢产物组的真菌人工染色体
BMC Genomics. 2015 Apr 29;16(1):343. doi: 10.1186/s12864-015-1561-x.
4
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