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使用多种测序技术构建蝙蝠白鼻综合征病原体——毁灭拟裸球壳菌的高质量基因组

Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome.

作者信息

Drees Kevin P, Palmer Jonathan M, Sebra Robert, Lorch Jeffrey M, Chen Cynthia, Wu Cheng-Cang, Bok Jin Woo, Keller Nancy P, Blehert David S, Cuomo Christina A, Lindner Daniel L, Foster Jeffrey T

机构信息

Department of Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, New Hampshire, USA.

Center for Forest Mycology Research, Northern Research Station, U.S. Forest Service, Madison, Wisconsin, USA.

出版信息

Genome Announc. 2016 Jun 30;4(3):e00445-16. doi: 10.1128/genomeA.00445-16.

DOI:10.1128/genomeA.00445-16
PMID:27365344
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4929507/
Abstract

White-nose syndrome has recently emerged as one of the most devastating wildlife diseases recorded, causing widespread mortality in numerous bat species throughout eastern North America. Here, we present an improved reference genome of the fungal pathogen Pseudogymnoascus destructans for use in comparative genomic studies.

摘要

白鼻综合征最近已成为有记录以来最具毁灭性的野生动物疾病之一，在北美东部的众多蝙蝠物种中造成了广泛的死亡。在此，我们提供了一种用于比较基因组研究的真菌病原体——毁灭假裸囊菌的改进参考基因组。

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Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome.使用多种测序技术构建蝙蝠白鼻综合征病原体——毁灭拟裸球壳菌的高质量基因组
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本文引用的文献

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White-nose syndrome without borders: Pseudogymnoascus destructans infection tolerated in Europe and Palearctic Asia but not in North America.白鼻综合征无国界：欧洲和古北亚地区耐受毁灭假裸囊菌感染，但北美不然。
Sci Rep. 2016 Jan 29;6:19829. doi: 10.1038/srep19829.
2
Widespread Bat White-Nose Syndrome Fungus, Northeastern China.中国东北地区广泛存在的蝙蝠白鼻综合征真菌。
Emerg Infect Dis. 2016 Jan;22(1):140-2. doi: 10.3201/eid2201.151314.
3
Fungal artificial chromosomes for mining of the fungal secondary metabolome.用于挖掘真菌次级代谢产物组的真菌人工染色体
BMC Genomics. 2015 Apr 29;16(1):343. doi: 10.1186/s12864-015-1561-x.
4
White-Nose Syndrome fungus introduced from Europe to North America.白鼻综合征真菌从欧洲传入北美。
Curr Biol. 2015 Mar 16;25(6):R217-R219. doi: 10.1016/j.cub.2015.01.047.
5
White-nose syndrome initiates a cascade of physiologic disturbances in the hibernating bat host.白鼻综合征会在冬眠的蝙蝠宿主中引发一系列生理紊乱。
BMC Physiol. 2014 Dec 9;14:10. doi: 10.1186/s12899-014-0010-4.
6
Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.Pilon：一种用于全面微生物变异检测和基因组组装改进的集成工具。
PLoS One. 2014 Nov 19;9(11):e112963. doi: 10.1371/journal.pone.0112963. eCollection 2014.
7
Draft Genome Sequences of Human Pathogenic Fungus Geomyces pannorum Sensu Lato and Bat White Nose Syndrome Pathogen Geomyces (Pseudogymnoascus) destructans.人类致病真菌泛裸囊菌复合种及蝙蝠白鼻综合征病原体毁灭裸囊菌（假裸囊菌属）的基因组序列草图
Genome Announc. 2013 Dec 19;1(6):e01045-13. doi: 10.1128/genomeA.01045-13.
8
Nonhybrid, finished microbial genome assemblies from long-read SMRT sequencing data.非杂交、基于长读长 SMRT 测序数据的完成微生物基因组组装。
Nat Methods. 2013 Jun;10(6):563-9. doi: 10.1038/nmeth.2474. Epub 2013 May 5.
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GapFiller: a de novo assembly approach to fill the gap within paired reads.GapFiller：一种从头开始的组装方法，用于填补配对读取中的缺口。
BMC Bioinformatics. 2012;13 Suppl 14(Suppl 14):S8. doi: 10.1186/1471-2105-13-S14-S8. Epub 2012 Sep 7.
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Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome.温度依赖性生长的 Geomyces destructans，这种真菌会引起蝙蝠白鼻综合征。
PLoS One. 2012;7(9):e46280. doi: 10.1371/journal.pone.0046280. Epub 2012 Sep 28.