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营养不良作为智力发育迟缓的一个原因:一项基于印度喜马拉雅山地区人群的研究。

Malnutrition as a cause of mental retardation: A population-based study from Sub-Himalayan India.

作者信息

Raina Sunil Kumar, Sharma Shailja, Bhardwaj Ashok, Singh Mitasha, Chaudhary Sanjeev, Kashyap Vipasha

机构信息

Department of Community Medicine, Dr. RP Government Medical College, Tanda, Himachal Pradesh, India.

Department of Pediatrics, Dr. RP Government Medical College, Tanda, Himachal Pradesh, India.

出版信息

J Neurosci Rural Pract. 2016 Jul-Sep;7(3):341-5. doi: 10.4103/0976-3147.182776.

Abstract

BACKGROUND

Mental retardation is one of the most common disabilities of childhood. The research on childhood malnutrition and its relationship with cognitive functioning suggests that malnutrition alone does not cause mental retardation.

OBJECTIVE

To identify the relation between malnutrition and cognition among children from a Sub-Himalayan state in North India.

MATERIALS AND METHODS

A two-phase cross-sectional study was conducted in the rural, urban, and slum area of district Kangra. A 30-cluster sampling technique was used to screen a population of children 1-10 years of age from five randomly selected panchayats (village government units) of district Kangra. The screening was based on a modified version of the ten questions screen, adapted to the local population. In the first phase, a door-to-door survey was done to identify suspects of mental retardation. In the second phase, the children found positive in the first phase were called for clinical examination to confirm mental retardation. Anthropometric assessment of all study children was done by measuring weight and height. The nutritional assessment was done by categorizing them according to Waterlow classification for malnutrition.

RESULTS

Out of the total 5300 children, 1.7% were diagnosed as mentally retarded. No positive association was reported with different types of malnutrition and mental retardation. A weakly positive association existed between nutritional status and mental retardation (correlation coefficient-0.04). Children who were both wasted and stunted had the highest risk (odds ratio, 95% confidence interval - 5.57, 2.29-10.36) of mental retardation as compared to normal.

CONCLUSION

Malnutrition may be one of the causes but certainly not the only cause of mental retardation. Other causes may be contributing more significantly toward it.

摘要

背景

智力发育迟缓是儿童期最常见的残疾之一。关于儿童营养不良及其与认知功能关系的研究表明,单纯营养不良不会导致智力发育迟缓。

目的

确定印度北部喜马拉雅山地区一个邦儿童营养不良与认知之间的关系。

材料与方法

在康格拉县的农村、城市和贫民窟地区进行了一项两阶段横断面研究。采用30群抽样技术,从康格拉县随机选取的5个村委会(村级政府单位)中筛查1至10岁的儿童群体。筛查基于根据当地人群改编的十个问题筛查的修改版本。在第一阶段,进行了挨家挨户的调查以确定智力发育迟缓的疑似病例。在第二阶段,将在第一阶段中检测为阳性的儿童召集进行临床检查以确诊智力发育迟缓。通过测量体重和身高对所有研究儿童进行人体测量评估。通过根据沃特洛营养不良分类法对他们进行分类来进行营养评估。

结果

在总共5300名儿童中,1.7%被诊断为智力发育迟缓。未报告不同类型的营养不良与智力发育迟缓之间存在正相关。营养状况与智力发育迟缓之间存在微弱的正相关(相关系数为-0.04)。与正常儿童相比,既消瘦又发育迟缓的儿童患智力发育迟缓的风险最高(优势比,95%置信区间 - 5.57,2.29 - 10.36)。

结论

营养不良可能是智力发育迟缓的原因之一,但肯定不是唯一原因。其他原因可能对其影响更大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca3/4898100/1a04ae38d7f8/JNRP-7-341-g004.jpg

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