Jain Deepanshu, Thosani Nirav, Singhal Shashideep
Department of Internal Medicine, Albert Einstein medical center, Philadelphia, PA, USA.
Division of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, Houston, TX, USA.
Therap Adv Gastroenterol. 2016 Jul;9(4):635-47. doi: 10.1177/1756283X16645050. Epub 2016 May 1.
Gastrointestinal bleeding can range from grossly visible blood in stool or vomitus to microscopic bleed. However, any kind of bleeding can lead to potential life-threatening consequences. A small proportion of patients with gastrointestinal bleeding remain refractory to initial endoscopic hemostasis. While some are successfully managed by repeat endoscopic intervention, a few fail to respond or are not amenable to endoscopic hemostasis. As of now, the next level of intervention is passed on to either surgeons or interventional radiologists. There is new evidence suggesting the increased utility of endoscopic ultrasound (EUS) in diagnosis and treatment of culprit vascular lesions across the gut. In addition, EUS-assisted technique has also been used in the primary prevention of bleeding from gastroesophageal varices. In this review article, we have summarized case series and reports describing the use of EUS-assisted hemostasis. Indications, techniques, complications and success rates reported are discussed. While most of the authors describe their experience with primary and secondary treatment of gastric varices, treatment of other gastrointestinal lesions with EUS assisted hemostatic techniques is also discussed.
胃肠道出血的范围可从粪便或呕吐物中肉眼可见的血液到显微镜下的出血。然而,任何类型的出血都可能导致潜在的危及生命的后果。一小部分胃肠道出血患者对初始内镜止血仍无反应。虽然一些患者通过重复内镜干预成功得到治疗,但仍有少数患者无反应或不适合内镜止血。截至目前,下一步的干预措施转交给外科医生或介入放射科医生。有新证据表明,内镜超声(EUS)在诊断和治疗全肠道的可疑血管病变方面的应用有所增加。此外,EUS辅助技术也已用于食管胃静脉曲张出血的一级预防。在这篇综述文章中,我们总结了描述EUS辅助止血应用的病例系列和报告。讨论了所报告的适应证、技术、并发症和成功率。虽然大多数作者描述了他们在胃静脉曲张一级和二级治疗方面的经验,但也讨论了用EUS辅助止血技术治疗其他胃肠道病变的情况。