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具有印戒细胞形态的胶质母细胞瘤:一项诊断挑战。

Glioblastoma with signet ring cell morphology: A diagnostic challenge.

作者信息

Krishnamoorthy Naveen, Veldore Vidya, Sridhar P S, Govindrajan M J, Prabhudesai Shilpa, Hazarika Digantha, Ajaikumar B S

机构信息

Department of Histopathology, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka, India.

Department of Research and Development, Triesta Reference Laboratory, HCG Bangalore Institute of Oncology, Bengaluru, Karnataka, India.

出版信息

Asian J Neurosurg. 2016 Jul-Sep;11(3):319-20. doi: 10.4103/1793-5482.149998.

Abstract

Glioblastoma (WHO Grade IV), the most frequent malignant brain tumor, can have varied morphologic variations like epithelial/glandular structures, granular cells, and lipidized cells. Glioblastoma with signet ring cell morphology is very unusual and can mimic a metastatic carcinoma. These rare tumors may be just a morphological variant or may signify a different carcinogenic pathway.

摘要

胶质母细胞瘤(世界卫生组织IV级)是最常见的恶性脑肿瘤,可呈现多种形态学变异,如上皮/腺结构、颗粒细胞和脂质化细胞。具有印戒细胞形态的胶质母细胞瘤非常罕见,可酷似转移性癌。这些罕见肿瘤可能只是一种形态学变异,也可能意味着不同的致癌途径。

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