Di Giammarco Gabriele, Marinelli Daniele, Foschi Massimiliano, Di Mauro Michele
Department of Cardiac Surgery, University 'G. D'Annunzio', Chieti, Italy.
J Cardiovasc Med (Hagerstown). 2017 May;18(5):295-304. doi: 10.2459/JCM.0000000000000401.
Transit-time flow measurement (TTFM) is a reliable method to check the graft function intraoperatively in coronary surgery. The given parameters are: Mean Graft Flow (MGF); Pulsatility Index (PI) and Insufficiency Ratio (%BF). Some cutoffs of these parameters have been identified as predictors for unfair 1-y clinical outcome: mean graft flow (MGF) less than 20 ml/min and high pulsatility index greater than 5. Other cutoffs have been found as related to postoperative angiography: MGF 15 ml/min or less and pulsatility index at least 3 (sensitivity 94%; specificity 61%); MGF less than 15 ml/min and pulsatility index greater than 3 for left coronary artery or pulsatility index greater than 5 for right coronary artery (sensitivity 96%; specificity 77%); MGF 15 ml/min or less and pulsatility index at least 5.1 left coronary artery (sensitivity 98%; specificity 26%). Hence, with the need to improve the diagnostic accuracy of TTFM, high-resolution epicardic coronary ultrasound module has been added to graft flow evaluation providing 2D ultrasound imaging (either in short-axis or long-axis) and color-flow mapping, allowing an accurate morphological evaluation of body graft and anastomosis. An intraoperative method aimed to verify coronary grafts should be easy to handle, not time consuming, minimally invasive, easily meaningful and relatively cheap; in addition, it should offer objective parameters more than qualitative criteria. We herein report the results of our experience with intraoperative graft verification with TTFM and high-resolution imaging along with a systematic review of the literature in this field with the aim to provide a road map to be followed.
渡越时间血流测量(TTFM)是一种在冠状动脉手术中术中检查移植物功能的可靠方法。给定的参数有:平均移植物血流(MGF);搏动指数(PI)和反流率(%BF)。这些参数的一些临界值已被确定为1年临床结果不佳的预测指标:平均移植物血流(MGF)小于20毫升/分钟和高搏动指数大于5。还发现其他临界值与术后血管造影有关:MGF为15毫升/分钟或更低且搏动指数至少为3(敏感性94%;特异性61%);左冠状动脉MGF小于15毫升/分钟且搏动指数大于3或右冠状动脉搏动指数大于5(敏感性96%;特异性77%);左冠状动脉MGF为15毫升/分钟或更低且搏动指数至少为5.1(敏感性98%;特异性26%)。因此,由于需要提高TTFM的诊断准确性,高分辨率心外膜冠状动脉超声模块已被添加到移植物血流评估中,提供二维超声成像(短轴或长轴)和彩色血流图,从而能够对身体移植物和吻合口进行准确的形态学评估。一种旨在验证冠状动脉移植物的术中方法应该易于操作、不耗时、微创、易于理解且相对便宜;此外,它应该提供客观参数而非定性标准。我们在此报告我们使用TTFM和高分辨率成像进行术中移植物验证的经验结果,以及对该领域文献的系统综述,目的是提供一个可遵循的路线图。